摘要
目的分析妊娠期干眼综合征患者泪液状态与视觉质量的相关性。方法比较妊娠期干眼综合征患者50例(干眼组)和正常妊娠期妇女50例(对照组)的泪液状态和视觉质量指标,采用Pearson相关分析视觉质量与其他指标的相关性。结果与对照组相比,干眼组眼表疾病指数评分、客观散射指数(OSI)、角膜荧光素染色评分升高(P<0.01),泪膜破裂时间(BUT)、调制传递函数(MTF)截止频率、斯特列尔比值(SR)、OV100%、OV20%、OV9%降低(P<0.01)。干眼组MTF截止频率、SR、OV100%、OV20%、OV9%与BUT呈正相关(r=0.712、0.624、0.627、0.610、0.712,P<0.01),OSI与BUT呈负相关(r=-0.735,P<0.01)。结论妊娠期干眼综合征患者的视觉质量低于正常妊娠期妇女,可能与妊娠期泪膜稳定性下降有关。
Objective To analyze the correlation between tear state and visual quality in dry eye syndrome patients during pregnancy.Methods The tear state and visual quality indexes of 50patients with dry eye syndrome during pregnancy(group A)and 50women without dry eye during pregnancy(group B)were compared.The correlation between visual quality and other indexes was analyzed by Pearson analysis.Results Compared to group B,ocular surface disease index score,corneal fluorescein staining score and objective scattering index(OSI)were higher,break up time(BUT),MTF cut-off frequency,Strelle ratio(SR),OV100%,OV20%and OV9%were lower in group A(P<0.05).MTF cut-off frequency,SR,OV100%,OV20%and OV9%were positively correlated with BUT(r=0.712,0.624,0.627,0.610and 0.712,P<0.01),and OSI was negatively correlated with BUT in group A(r=-0.735,P<0.01).Conclusion The visual quality of dry eye syndrome patients during pregnancy is lower than that of normal pregnancy women,which may be related to the decreased stability of tear film during pregnancy.
作者
叶芬
程友
黄振平
何晶
YE Fen;CHENG You;HUANG Zhenping(Post-doctoral Scientific Research Station,General Hospital of Eastern Theater Command,Nanjing 210000,CHINA)
出处
《江苏医药》
CAS
2023年第10期982-984,共3页
Jiangsu Medical Journal
基金
国家自然科学基金(81270979)。
