摘要
目的探究口腔显微镜下应用生物陶瓷材料IRoot BP Plus根尖屏障术治疗慢性根尖周炎伴根尖未闭合患者的效果。方法选取慢性根尖周炎伴根尖未闭合的患者60例作为研究对象,采用随机数字表分为3组,各20例。A组在常规治疗的基础上进行口腔显微镜下的IRoot BP Plus根尖屏障术治疗,B组进行常规治疗,C组在常规治疗的基础上进行根管填充治疗。比较3组口腔治疗操作时间和患者术后疼痛时间,治疗前后血清炎性因子[C反应蛋白(CRP)、白介素6(IL-6)、白介素1β(IL-1β)、肿瘤坏死因子α(TNF-α)]水平以及根尖周指数。结果A组术后疼痛时间显著短于B组和C组(均P<0.001),且B组术后疼痛时间又短于C组(P<0.001);治疗后1个月,A组血清CRP,IL-6,IL-1β和TNF-α水平均显著低于B组和C组(P<0.05或P<0.001);治疗后3个月及治疗后6个月,A组根尖周指数显著低于B组及C组(P<0.05或P<0.001)。结论口腔显微镜下生物陶瓷IRoot BP Plus根尖屏障术用于慢性根尖周炎伴根尖未闭合患者可缓解其术后疼痛,减轻炎症反应并改善根尖状况。
Objective To evaluate the effectiveness of bioceramic IRoot BP Plus apical barrier surgery under oral microscopy in patients with chronic apical periodontitis and open apices.Methods Sixty patients with chronic periapical periodontitis and open apices randomly received bioceramic IRoot BP Plus apical barrier surgery under oral microscopy(group A),routine treatment(group B),or root canal filling based on routine treatment(group C),with 20 patients in each group.The duration of treatment,postoperative pain time,serum levels of C-reactive protein(CRP),interleukin 6(IL-6),interleukin 1β(IL-1β)and tumor necrosis factor-α(TNF-α),and periapical index were compared among the three groups.Results The postoperative pain time in group A was shorter than that in groups B and C(P<0.001),and that in group B was shorter than that in group C(P<0.001).At 1 month after treatment,serum CRP,IL-6,IL-1βand TNF-αlevels in group A were lower than those in groups B and C(P<0.05 or P<0.001).At 3 and 6 months after treatment,periapical index in group A was lower than that in groups B and C(P<0.05 or P<0.001).Conclusion Bioceramic IRoot BP Plus apical barrier surgery under oral microscopy can relieve postoperative pain,reduce inflammatory response and improve apical status in patients with chronic apical periodontitis and open apices.
作者
孙瑗征
周志坤
王智
SUN Yuan-zheng;ZHOU Zhi-kun;WANG Zhi(Department of Dental Endodontics,Henan Saisi Stomatological Hospital,Zhengzhou 450000,China;Department of Periodontal Disease,Henan Saisi Stomatological Hospital,Zhengzhou 450000,China)
出处
《实用临床医学（江西）》
CAS
2023年第5期40-42,47,共4页
Practical Clinical Medicine
