摘要
目的分析间接血凝试验(IHA)在日本血吸虫病门诊筛查诊断中的效能。方法选取2021年12月至2023年1月于本站行日本血吸虫病筛查的300例居民,实施IHA与胶体金免疫渗滤斑点法(DIGFA)。以病原学检测(改良加藤厚涂片法合并尼龙绢集卵孵化法)为“金标准”,对比分析IHA、DIGFA在日本血吸虫病门诊筛查中的效能。结果以病原学检测为“金标准”,IHA的灵敏度、特异度、准确度分别为80.77%(21/26)、98.20%(273/278)、98.00%(294/300),明显高于DIGFA的23.08%(6/26)、93.13%(271/291)、92.33%(277/300),差异有统计学意义(P<0.05)。κ检验显示,IHA筛查日本血吸虫病与病原学检测结果具有极好的一致性(κ=0.864,P=0.000)。结论IHA在日本血吸虫病诊断中的特异度、准确度较高,可用于日本血吸虫病的早期门诊筛查。
Objective To analyze the efficacy of indirect hemagglutination test(IHA)in outpatient screening and diagnosis of schistosomiasis japonica.Methods 300 residents with screening for schistosomiasis japonica in our station from December 2021 to January 2023 were selected,and given IHA and dot immuno-gold filtration assay(DIGFA).Taking the pathogenic test(modified Kato thick smear method combined with nylon silk egg incubation method)as the gold standard,the efficacy of IHA and DIGFA in outpatient screening of schistosomiasis japonica was compared and analyzed.Results Taking the pathogenic test as the gold standard,the sensitivity,specificity and accuracy of IHA was 80.77%(21/26),98.20%(273/278)and 98.00%(294/300)respectively,signifiantly higher than 23.08%(6/26),93.13%(271/291)and 92.33%(277/300)of DIGFA(P<0.05).κ test showed that the results of IHA in screening for schistosomiasis japonica had excellent consistency with the pathogenic test(κ=0.864,P=0.000).Conclusions IHA has higher specificity and accuracy in the diagnosis of schistosomiasis japonica,which can be used for early outpatient screening of schistosomiasis japonica.
作者
占王园
张鸿
ZHAN Wangyuan;ZHANG Hong(Clinical Laboratory,Poyang County Schistosomiasis Control Station,Shangrao 333100,China)
出处
《临床医学工程》
2023年第11期1615-1616,共2页
Clinical Medicine & Engineering
关键词
日本血吸虫病
门诊筛查
间接血凝试验
灵敏度
特异度
Schistosomiasis japonica
Outpatient screening
Indirect hemagglutination test
Sensitivity
Specificity
