摘要
慢性前列腺炎/慢性盆腔疼痛综合征(chronic prostatitis/chronic pelvic pain syndrome,CP/CPPS)发病机制复杂、症状多,诊断和治疗存在一定的困难。针灸治疗是一种常见的慢性、疼痛性疾病的治疗方法,可以刺激CP/CPPS患者先天免疫细胞因子IL-6的免疫应答,降低TLR4表达,抑制NF-KB激活,下调IL-1β和IL-18水平,平衡多种细胞因子,从而抑制局部炎症,产生间接或直接的镇痛作用。本文综述了CP/CPPS的发病机制及梳理了针灸治疗CP/CPPS的作用途径,为进一步的研究提供依据。
Chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)represents the most common type of CP,characterized by complex pathogenesis and a wide array of symptoms,making diagnosis and treatment challenging.Acupuncture,a widely used treatment for chronic and painful conditions,has demonstrated clinical efficacy in restoring prostate function and enhancing the quality of life for affected patients.This article critically examines the intricate pathogenesis of CP/CPPS and explores the related therapeutic mechanisms of acupuncture.Additionally,it summarizes the advancements made in the last decades regarding the use of acupuncture for treating CP/CPPS and elucidates potential effect pathways,laying the groundwork for further fundamental research.
作者
杨宇
彭迅超
唐成林
Yang Yu;Xunchao Peng;Chenglin Tang(Acupuncture Department,Yongchuan Traditional Chinese Medicine Hospital Affiliated to Chongqing Medical University,Chongqing,China;College of Traditional Chinese Medicine,Chongqing Medical University,Chongqing,China)
基金
supported by Chongqing Municipal Famous TCM Department Construction Project(Chongqing Traditional Chinese Medicine(2022)No.2).
