摘要
肿瘤与双心疾病共病是临床常见状态,与肿瘤治疗及预后密切相关,探讨其核心病机及治法可为临床治疗带来新的思路和策略。认为心肾阳虚是双心疾病常见的核心病机之一,郁热毒闭是肿瘤生成及转移的核心病机,癌毒损络致血脉之心失荣,肺失宣降致神明之心郁结,从而导致或加重双心疾病。基于“以证统病”诊治思路探讨相关证治,辨证在前,四诊合参,明确核心病机及基本治则;辨病在后,识病佐证,兼顾疾病特殊性加减用药。实现肿瘤与双心疾病精准施治,减少多重用药副作用,冀以指导临床应用。
The co-occurrence of tumor and psycho-cardiological diseases,affecting both the physical and mental aspects of patients,is a common clinical condition that is closely related to tumor treatment and prognosis.Exploring its underlying mechanism and treatment methods can bring new ideas and strategies for clinical treatment.It is believed that heart-kidney yang deficiency is one of the common core mechanisms of psycho-cardiological diseases.Stagnation of heat and toxins is a core mechanism for tumor formation and metastasis.Additionally,cancer and drug toxicity contribute to the development of psycho-cardiological disease by impairing lung circulation.Cancerous toxins can damage the blood vessels,resulting in a diminished vitality in the heart of blood vessels.Simultaneously,lung qi failing in dispersing impairs the downward movement and causes stagnation in the heart of spirit.This process ultimately leads to the development or exacerbation of psycho-cardiological diseases.The author explores the diagnosis and treatment approach based on the “diagnosing and treating diseases according to syndroms” concept,focusing on related syndrom identification and treatment.The process begins with pattern identification,followed by comprehensive analysis of data gained by four diagnostic methods to clearly understand the core pathogenesis and basic treatment principles.After pattern identification,the focus shifts to recognizing the disease and providing additional evidence to support the diagnosis.Special attention is paid to adjusting the use of medication based on the disease's characteristics.This approach aims to achieve precise treatment for tumors and psycho-cardiological diseases,reducing the side effects of multiple medications,therefore to provide guidance for clinical application.
作者
韩欣璞
朱潇雨
许博文
李杰
HAN Xinpu;ZHU Xiaoyu;XU Bowen;LI Jie(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing,100053;Beijing University of Chinese Medicine)
出处
《中医杂志》
CSCD
北大核心
2023年第21期2248-2252,共5页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81774289,82074402)
国家重点研发计划(2018YFC1707405)
首都卫生发展科研专项(首发2022-1-4151)
国家中医药传承创新团队项目(ZYYCXTD-C-202205)
中央级公益性科研院所基本科研业务费专项资金资助(ZZ16-XRZ-037)
中国中医科学院科技创新工程(CI2021A01802)
广安门医院领航工程高层次人才团队培育项目。
关键词
肿瘤
双心疾病
共病
malignant tumor
psycho-cardiological disease
co-morbidity
