摘要
目的:观察体外冲击波治疗(ESWT)慢性非特异性下腰痛(NLBP)的临床疗效及对患者炎性因子、儿茶酚胺、腰盆区域组织血流量水平的影响。方法:采用随机数字表法,将2020-04-2023-04中国人民解放军南部战区总医院中医科收治的61例慢性非特异性下腰痛患者分为对照组(n=31)和观察组(n=30)。对照组采用常规物理治疗,观察组在对照组基础上予以ESWT,共治疗4周。观察两组患者治疗前后疼痛视觉评分量表(VAS评分)、Oswestry功能障碍指数(ODI)、罗兰·莫里斯残疾问卷(RMDQ)、炎性因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)]、儿茶酚胺[肾上腺素(Adr)、去甲肾上腺素(NE)]和腰盆区域组织血流量水平的变化并比较组间差异。结果:与治疗前比较,治疗后对照组和观察组VAS、ODI、RMDQ评分、TNF-α、IL-1β水平均降低(P<0.05),Adr、NE、腰盆区域组织血流量水平升高(P<0.05);与对照组治疗后比较,观察组ODI、RMDQ评分、TNF-α、IL-1β水平均降低(P<0.05),Adr、NE、腰盆区域组织血流量增加(P<0.05)。结论:ESWT治疗NLBP疗效确切,能提高肾上腺素水平,通过解除挛缩来介导抗炎作用,增加腰盆区域组织血流量,减轻患者疼痛,改善患者生活质量。
Objective:To observe the clinical efficacy of extracorporeal shock wave therapy(ESWT)in chronic non-specific low back pain(NLBP)and the effect on the levels of inflammatory factors,catecholamines and lumbovic tissue blood flow.Method:A random number table method was used to divide 61 patients with chronic non-specific low back pain from 2020-04 to 2023-04 into control group(n=31)and observation group(n=30).The control group was treated with conventional physiotherapy,and the observation group was given ESWT on the basis of the control group for a total of 4 weeks.The levels of pain visual score scale(VAS score),Oswestry dysfunction index(ODI),Roland Morris disability questionnaire(RMDQ),inflammatory factors including tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),catecholamines(epinephrine(Adr),norepinephrine(NE)),and tissue blood flow were observed in both groups.Results:Compared with before treatment,the levels of VAS,ODI,RMDQ,TNF-α and IL-1β were decreased(P<0.05),and the levels of Adr,NE and tissue blood flow were increased(P<0.05)after treatment in the control group and observation group,and compared with the control group,the ODI,RMDQ score,TNF-α and IL-1β levels in the observation group were decreased(P<0.05),and the Adr,NE level and tissue blood flow were increased(P<0.05).Conclusion:ESWT in the treatment of NLBP has a definite effect,can significantly reduce the pain of patients,increase the level of epinephrine,mediate the anti-inflammatory effect by relieving contractures,increase the blood flow of tissues in the lumbar and pelvic region,and improve the quality of life of patients.
作者
乔思竹
韦嵩
陈志煌
侯春福
李慧
QIAO Si-zhu;WEI Song;CHEN Zhi-huang;HOU Chun-fu;LI Hui(Department of Traditional Chinese Medicine,General Hospital of Southern Theater Command of PLA,Guangzhou 510000,China)
出处
《微循环学杂志》
2023年第4期56-59,63,共5页
Chinese Journal of Microcirculation
基金
国家自然科学基金项目(81573883)
广州市科技项目(202102080596)
广东省医学科学技术研究基金项目(B2021359,C2021117)。
