摘要
目的:探讨血栓弹力图(TEG)在冠状动脉旁路移植术个体化成分输血的应用价值。方法:选择2018—2020年入院行冠状动脉旁路移植术的患者,分为TEG指导组(TEG组)及传统常规凝血指导组(CCT组),每组随机抽取50例。比较2组患者围术期中红细胞(RBC)、冰冻血浆(FP)、血小板(PLT)、冷沉淀(CRY)输血量及输血不良反应发生率、再次手术率的差异。结果:TEG组及CCT组各血液成分的输血量比较,2组RBC输注总量差异无统计学意义(P>0.05);TEG组PLT、FP、CRY各输注总量均少于CCT组,差异有统计学意义(P<0.05);TEG组输血不良反应发生率较CCT组明显减少(P<0.05);2组间再次手术率差异无统计学意义(P>0.05)。结论:TEG在冠状动脉旁路移植术个体化成分输血中,可通过合理调整输注剂量,提高输血治疗的有效性、安全性,降低输血不良反应,节约临床用血。
Objective To investigate the application value of thromboelastogram(TEG) in individual component transfusion in coronary artery bypass grafting.Methods The patients who were admitted to our hospital for coronary artery bypass grafting from 2018 to 2020 were divided into TEG guidance group(TEG group) and conventional coagulation guidance group(CCT group). A total of 50 patients were randomly selected from each group. The blood transfusion volume of red blood cell(RBC), frozen plasma(FP), platelet(PLT), cryoprecipitate(CRY), the incidence of adverse blood transfusion reaction and the reoperation rate were compared between the two groups.Results There was no significant difference in the total amount of RBC transfusion between TEG group and CCT group(P>0.05). The total amount of PLT, FP and CRY transfusion in TEG group was less than those in CCT group, with statistically significant difference(P < 0.05). The incidence of adverse transfusion reactions in TEG group was significantly lower than that in CCT group(P < 0.05). There was no significant difference in reoperation rate between the two groups(P>0.05).Conclusion TEG in individual component transfusion of coronary artery bypass grafting could improve the effectiveness and safety of transfusion therapy, reduce the adverse reactions of transfusion and save the clinical use of blood by adjusting the infusion dose reasonably.
作者
陈瑜
温燕华
邱芳
邹丽萍
温小云
唐志贤
余俊建
CHEN Yu;WEN Yanhua;QIU Fang;ZOU Liping;WEN Xiaoyun;TANG Zhixian;YU Junjian(Department of Blood Transfusion,the First Affiliated Hospital of Gannan Medical College,Ganzhou,341000,China;Department of Thoracic Surgery,the First Affiliated Hospital of Gannan Medical College)
出处
《临床血液学杂志》
2023年第10期751-754,共4页
Journal of Clinical Hematology
基金
赣州市指导性科技计划(No:GZ2018ZSF049)。
关键词
血栓弹力图
冠状动脉旁路移植术
输血
围术期
thromboelastogram
coronary artery bypass grafting
blood transfusion
perioperative period
