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脱细胞异体真皮联合自体刃厚皮片移植修复小儿头面颈躯深度烧伤创面的效果研究 被引量:1

Effect of acellular allogeneic dermis combined with autologous blade thickness skin graft in repairing deep burn wounds of head,face,neck and torso in children
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摘要 目的 探讨脱细胞异体真皮联合自体刃厚皮片移植修复小儿头面颈躯深度烧伤创面的临床效果。方法 选取2019年6月至2021年5月我院收治的62例头面颈躯深度烧伤儿童作为研究对象,按照随机数字表法分为观察组(n=31)和对照组(n=31)。观察组采用脱细胞异体真皮联合自体刃厚皮片移植修复,对照组仅采用自体刃厚皮片移植。比较2组患儿皮片成活率、创面愈合时间、不良反应(疼痛、创面感染等)发生率;比较2组患儿创面恢复情况、瘢痕形成状况及治疗满意率。结果 2组患儿术后皮片成活率和不良反应发生率比较差异均无统计学意义(P>0.05);观察组患儿术后创面愈合时间明显短于对照组(P<0.05)。对照组患儿术后温哥华瘢痕量表(VSS)评分高于观察组,差异有统计学意义(P<0.05)。术后6个月观察组患儿瘢痕形成状况优于对照组,差异有统计学意义(P<0.05)。术后观察组患儿治疗满意率高于对照组,差异有统计学意义(P<0.05)。结论 头面颈躯深度烧伤患儿采用脱细胞异体真皮联合自体刃厚皮片移植修复术治疗创面愈合更快,愈合效果更好,术后瘢痕更小,患儿满意率更高。 Objective To investigate the clinical effect of acellular allogenic dermis combined with autologous blade thickness skin graft in repairing deep burn wounds of head,face,neck and torso in children.Methods A total of 62 children with deep burns of head,face,neck and torso admitted to our hospital from June 2019 to May 2021 were selected as the research objects,and they were divided into the observation group(n=31)and the control group(n=31)according to the random number table method.The observation group received acellular allogenic dermis combined with autologous blade thickness skin graft,while the control group received only autologous blade thickness skin graft.The skin graft survival rate,wound healing time,incidence of adverse reactions(pain,wound infection,etc.),wound recovery,scar formation and treatment satisfaction rate of the two groups were compared.Results There was no statistically significant difference in the skin graft survival rate or incidence of adverse reactions after operation between the observation group and the control group(P>0.05).The postoperative wound healing time of the observation group was significantly shorter than that of the control group(P<0.05).The Vancouver scar scale(VSS)score of the control group was higher than that of the observation group,and the difference was statistically significant(P<0.05).The scar formation 6 months after operation of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).The treatment satisfaction rate after operation of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The acellular allogeneic dermis combined with autologous blade thickness skin graft in the treatment of children with deep burns of head,face,neck and torso has faster wound healing,better healing effect,smaller postoperative scar and higher satisfaction rate.
作者 杜文茜 陈文娣 吴婷婷 徐达 DU Wen-qian;CHEN Wen-di;WU Ting-ting;XU Da(Department of Burn and Plastic Surgery,the 71st Group Military Hospital,Xuzhou Jiangsu 221000,China)
机构地区 陆军第
出处 《局解手术学杂志》 2023年第11期990-994,共5页 Journal of Regional Anatomy and Operative Surgery
基金 军区医药卫生科研基金(09Z007)。
关键词 烧伤 脱细胞异体真皮 自体刃厚皮片 移植 瘢痕 burn acellular allogeneic dermis autologous blade thickness skin graft scar
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