摘要
Regulated cell death is a genetically determined form of programmed cell death that commonly occurs during the development of living organisms.This process plays a crucial role in modulating homeostasis and is evolutionarily conserved across a diverse range of living organisms.Ferroptosis is a classic regulatory mode of cell death.Extensive studies of regulatory cell death in Alzheimer’s disease have yielded increasing evidence that fe rroptosis is closely related to the occurrence,development,and prognosis of Alzheimer’s disease.This review summarizes the molecular mechanisms of ferroptosis and recent research advances in the role of ferro ptosis in Alzheimer’s disease.Our findings are expected to serve as a theoretical and experimental foundation for clinical research and targeted therapy for Alzheimer’s disease.
基金
supported by the National Natural Science Foundation of China,No.81501106(to CF)
Fund of Taishan Scholar Project(to CF)
the Natural Science Foundation of Shandong Province,No.ZR2020QH106(to YH)
the Medical and Health Science and Technology Development Plan of Shandong Province,No.202203010799(to QS)。
