摘要
川崎病(Kawasaki disease,KD)是一种病因不明的免疫系统异常活化导致的血管炎性综合征。冠状动脉病变(coronary arterial lesion,CAL)患者如果没有经过有效治疗,其发生率能够达到25%。患者恢复期阶段疾病损伤仍然持续存在,时间甚至长达数年,不断损害患者的血管健康,增加血栓形成率,诱发心肌梗死等各种缺血性心脏病。本研究回顾分析1例13岁、因“胸闷、呼吸困难”入院患儿的临床资料,追问病史,同时检索相关文献并进行总结。患儿心脏冠状动脉CTA提示双侧冠状动脉瘤并右冠血栓形成,心电图示前间壁的心肌缺血,诊断为严重冠状动脉病变,结合既往病史,考虑患儿胸闷、呼吸困难为表现的心血管事件的发生与可能幼时川崎病并发的严重冠状动脉病变相关。
Kawasaki disease(KD)is a vasculitic syndrome caused by abnormal activation of the immune system of unknown etiology.Without effective arterial therapy,the incidence of coronary artery disease(CAL)can reach 25%.In the recovery stage,the disease damage still persists,even for several years,which continuously damages the blood vessel health of patients,increases the rate of thrombosis,and induces various ischemic heart diseases such as myocardial infarction.This study reviewed and analyzed the clinical data of a 13-year-old child admitted to hospital due to"chest tightness and dyspnea",inquired the medical history,searched the relevant literature and made a summary.CTA indicated bilateral coronary aneurysms and right coronary thrombosis in the patient,and electrocardiogram showed myocardial ischemia in the anterior space wall,indicating severe coronary artery disease.Combined with previous medical history,it was considered that the occurrence of cardiovascular events manifested by chest tightness and dyspnea in children was related to the possible severe coronary artery lesions complicated with Kawasaki disease in childhood.
作者
高晓音
秦道刚
吕慧敏
蒋树娟
王军
范玲玲
GAO Xiaoyin;QIN Daogang;LYU Huimin;JIANG Shujuan;WANG Jun;FAN Lingling(Department of Pediatrics,Liaocheng People′s Hospital,Liaocheng,Shandong Province,252000 China)
出处
《系统医学》
2023年第16期140-144,共5页
Systems Medicine
关键词
冠状动脉瘤
血栓
冠状动脉病变
64层冠状动脉CTA川崎病
Coronary aneurysm
Blood clot
Coronary artery disease
64-layer coronary artery CTA Kawasaki disease
