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口服孕激素与曼月乐环对预防宫腔镜下子宫内膜息肉电切术后复发的效果对比 被引量:1

Comparison of the effect of oral progesterone or mirena ring on the prevention of recurrence after hysteroscopic electroresection ofendometrial polyps
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摘要 目的探讨口服孕激素与左炔诺孕酮宫内缓释系统(曼月乐环)对预防宫腔镜下子宫内膜息肉电切术后复发的效果。方法选取40例行宫腔镜下子宫内膜息肉电切术治疗患者,采用随机数字表法分组,各20例。对照组实施口服孕激素干预治疗,研究组实施曼月乐环干预治疗。对比两组子宫内膜厚度、月经量、疾病复发率及不良反应发生情况。结果治疗半年及1年后研究组子宫内膜厚度薄于对照组(P<0.05)。研究组患者月经量评分低于对照组(P<0.05)。研究组复发率为5.00%,对照组复发率为15.00%,对比差异无统计学意义(P>0.05)。研究组不良反应发生率低于对照组,但对比差异无统计学意义(P>0.05)。结论与口服孕激素相比,对行宫腔镜下子宫内膜息肉电切术治疗患者实施曼月乐环干预效果更为明显,可有效改善子宫内膜厚度,减少或避免疾病复发,且具有安全性。 Objective To investigate the effect of oral progesterone and levonorgestrel intrauterine sustained release system(Mirena ring)on the prevention of recurrence after hysteroscopic electroresection of endometrial polyps.Methods 40 patients undergoing hysteroscopic electroresection of endometrial polyps were selected and divided into 20 patients by random number table method.The control group was treated with oral progesterone intervention,and the study group was treated with mirena ring intervention.Endometrial thickness,menstrual volume,disease recurrence rate and adverse reactions were compared between the two groups.Results After six months and one year of treatment,the endometrial thickness of the study group was thinner than that of the control group(P<0.05).The score of menstrual volume in the study group was lower than that in the control group(P<0.05).The recurrence rate was 5.00%in the study group and 15.00%in the control group,with no statistical significance(P>0.05).The incidence of adverse reactions in the study group was lower than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion Compared with oral progesterone,the intervention effect of mirena ring on patients undergoing hysteroscopic electroresection of endometrial polyps is more obvious,which can effectively improve endometrial thickness,reduce or avoid disease recurrence,and has safety.
作者 曾志红 Zeng Zhihong(Department of Obstetrics and Gynecology Outpatient,Dongguan Hospital of Integrated Traditional Chinese and Western Medicine,Dongguan 523000,China)
出处 《实用妇科内分泌电子杂志》 2023年第21期57-59,共3页 Electronic Journal of Practical Gynecological Endocrinology
关键词 子宫内膜息肉 宫腔镜下子宫内膜息肉电切术 孕激素 曼月乐环 Endometrial polyps Hysteroscopic electroresection of endometrial polyps Progesterone Mirena ring
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