摘要
目的分析脑卒中患者住院期间静脉血栓栓塞症(VTE)发生率及其影响因素。方法选取江苏省人民医院2019-07—2022-07收治的96例脑卒中患者,根据住院期间VTE发生情况分为VTE组(n=26)和非VTE组(n=70)。比较2组临床资料,采用多因素Logistic回归分析VTE的影响因素。结果VTE组年龄、NIHSS评分、血清D-D水平、女性、长期卧床、吸烟史、既往VTE史、使用脱水剂、股静脉穿刺/置管、下肢肿胀的占比高于非VTE组,差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,年龄(OR=1.633,95%CI:1.108~2.407)、NIHSS评分(OR=1.809,95%CI:1.156~2.831)、血清D-D(OR=1.493,95%CI:1.077~2.070)、长期卧床情况(OR=2.240,95%CI:1.245~4.030)、既往VTE史(OR=2.711,95%CI:1.239~5.932)、股静脉穿刺/置管(OR=2.465,95%CI:1.188~5.115)、下肢肿胀(OR=2.933,95%CI:1.357~6.339)是脑卒中患者住院期间VTE的影响因素(P<0.05)。结论年龄较大、NIHSS评分高、血清D-D水平高、长期卧床及存在下肢肿胀、既往VTE史、股静脉穿刺/置管的脑卒中患者更容易发生VTE,可对该类患者进行早期干预及防治,以降低VTE发生风险。
Objective To analyze the incidence of venous thromboembolism(VTE)in patients with cerebral apoplexy during hospitalization and its influencing factors.Methods A total of 96 cases of stroke patients admitted to the Emergency Department of Jiangsu Provincial People’s Hospital from July 2019 to July 2022 were selected.According to the incidence of VTE during hospitalization,they were divided into VTE group(n=26)and non-VTE group(n=70).The clinical data of the two groups were compared,and the influencing factors for VTE were determined by multivariate Logistic regression analysis.Results The age,NIHSS score,serum D-D level,the proportion of female,long-term bed rest,smoking history,previous VTE history,use of dehydrating agent,femoral vein puncture/catheterization,lower limb swelling in VTE group were higher than those in non-VTE group,and the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that age(OR=1.633,95%CI:1.108-2.407),NIHSS score(OR=1.809,95%CI:1.156-2.831),serum D-D(OR=1.493,95%CI:1.077-2.070),long-term bed rest(OR=2.240,95%CI:1.245-4.030),previous VTE history(OR=2.711,95%CI:1.239-5.932),femoral vein puncture/catheterization(OR=2.465,95%CI:1.188-5.115)and lower limb swelling(OR=2.933,95%CI:1.357-6.339)were the influencing factors for VTE in stroke patients during hospitalization(P<0.05).Conclusion Stroke patients with older age,high NIHSS score,serum D-D level,long-term bed rest and lower limb swelling,previous history of VTE,and femoral vein puncture/catheterization are more likely to develop VTE.Early intervention and prevention can be carried out for these patients to reduce the risk of VTE.
作者
李欢欢
朱玉婷
朱欢欢
LI Huanhuan;ZHU Yuting;ZHU Huanhuan(Jiangsu Provincial People’s Hospital,Nanjing 210000,China;Lishui District Hospital of Traditional Chinese Medicine,Nanjing 210000,China;Dncm Tower Hospital,School of Medicine,Nanjing University,Nanjing 210000,China)
出处
《中国实用神经疾病杂志》
2023年第12期1463-1467,共5页
Chinese Journal of Practical Nervous Diseases
基金
江苏省卫生健康委科研项目(编号:H2019108)。
关键词
脑卒中
住院期间
静脉血栓栓塞症
血液高凝
影响因素
Cerebral apoplexy
During hospitalization
Venous thromboembolism
Hypercoagulation of blood
Influencing factor
