摘要
目的分析炔雌醇环丙孕酮片联合二甲双胍治疗多囊卵巢综合征的临床效果。方法选取69例多囊卵巢综合征患者,根据随机数字表法分为对照组(34例)与试验组(35例)。对照组采用炔雌醇环丙孕酮片治疗,试验组在对照组基础上联合二甲双胍治疗。比较两组临床疗效、治疗前后血清性激素水平。结果试验组总有效率97.1%高于对照组的82.4%,差异有统计学意义(P<0.05)。治疗前,两组血清促黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)、雌二醇(E2)水平比较,差异无统计学意义(P>0.05);治疗后,试验组E2水平高于对照组,LH、FSH、T水平低于对照组,差异有统计学意义(P<0.05)。结论炔雌醇环丙孕酮片联合二甲双胍治疗多囊卵巢综合征疗效显著,可有效改善患者性激素水平,值得临床推广。
Objective To analyze the clinical effect of ethinestradiol cyproterone tablets combined with metformin in the treatment of polycystic ovary syndrome.Methods 69 patients with PCoS were divided into control group(34 cases)and experimental group(35 cases)according to random number table method.The control group was treated with ethinestradiol cyproterone tablets,and the experimental group was treated with metformin on the basis of the control group.The clinical efficacy and serum sex hormone levels before and after treatment were compared between the two groups.Results The total effective rate of experimental group was 97.1%higher than that of control group(82.4%),and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in serum luteinizing hormone(LH),follicle-stimulating hormone(FSH),testosterone(T)and estradiol(E2)levels between 2 groups(P>0.05).After treatment,E,level of experimental group was higher than that of control group,LH,FSH,Tlevel was lower than that of control group,the difference was statistically significant(P<o.05).Conclusion The combination of ethinylestradiol cyproterone and metformin in the treatment of polycystic ovary syndrome is effective and can effectively improve the level of sex hormones in patients,which is worthy of clinical promotion.
作者
何远红
陈惠丽
He Yuanhong;Chen Huili(Department of Obstetrics and Gynecology,Shenzhen Baoan District Central Hospital,Shenzhen 518100,China)
出处
《实用妇科内分泌电子杂志》
2023年第23期76-78,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
多囊卵巢综合征
炔雌醇环丙孕酮片
二甲双胍
性激素
临床疗效
Polycystic ovary syndrome
Ethinestradiol cyproterone tablets
Metformin
Sex hormone
Clinical effect
