摘要
肝脏是结直肠癌血行转移最主要的靶器官,约15%~25%结直肠癌患者在确诊时即合并有肝转移,为探讨直肠癌肝转移灶的治疗方式,本文报道1例直肠癌肝转移患者,分期先行直肠癌根治术,术后1个月予卡培他滨联合奥沙利铂(XELOX方案)+贝伐珠单抗2个周期的新辅助治疗后,行Glisson蒂横断式荧光腹腔镜左半肝切除,术后病理提示无癌细胞,提示病理完全缓解(pathological complete response,pCR),术后5个月复查未见复发。
The liver is the most important target organ for blood metastasis of colorectal cancer.15%~25%of colorectal cancer patients have liver metastasis at the time of diagnosis.In order to discuss the treatment of liver metastasis of rectal cancer,this paper reported a case of liver metastasis from rectal cancer,who underwent radical resection of rectal cancer by stages.One month after the operation,he received two cycles of neoadjuvant chemotherapy with capecitabine plus oxaliplatin(XELOX)and bevacizumab,and then underwent laparoscopic left hemihepatectomy with fluorescence staining via Glisson pedicle transection.Postoperative pathology showed that there were no cancer cells,indicating pathological complete response(pCR).No recurrence was found in 5 months after the operation.
作者
马东恒
钟家健
陈斯聪
MA Dong-heng;ZHONG Jia-jian;CHEN Si-cong(Hepatobiliary and Pancreatic Surgery,Union Shenzhen Hospital,Huazhong University of Science and Technology,Guangdong Shenzhen 518052,China)
出处
《循证医学》
2023年第4期252-256,共5页
The Journal of Evidence-Based Medicine
基金
深圳市南山区科技计划区属事业单位研发资助项目(2018077)。