摘要
目的 探究除热滋阴方结合安宫黄体酮对阴虚内热型崩漏的治疗效果。方法 纳入61例阴虚内热型崩漏患者(2019年3月-2021年1月),以随机数字表法将其分成观察组和对照组,对照组(31例)采取雌激素与安宫黄体酮结合治疗,观察组患者(30例)在对照组治疗基础上联合除热滋阴方进行治疗。比较两组患者临床疗效、治疗前后中医证候(阴道出血量多或淋漓不尽、五心烦热、潮热颧红、咽燥口干、大便干燥等)积分变化及血清雌二醇(E_(2))、促卵泡生成激素(FSH)、促黄体生成激素(LH)、血红蛋白(Hb)水平变化、不良反应。结果 相较于对照组,观察组患者临床疗效更高(P<0.05)。治疗前,两组患者中医证候(阴道出血量多或淋漓不尽、五心烦热、潮热颧红、咽燥口干、大便干燥等)积分、E_(2)、FSH、LH、Hb等指标比较无显著差异(P>0.05);治疗后,两组患者中医证候积分、E_(2)、FSH、LH、Hb等指标均得到改善,观察组患者治疗后上述指标均优于对照组(P<0.05);对照组出现1例恶心、1例呕吐、1例头晕,而观察组出现1例乏力与1例头晕,患者不良反应可自行缓解(P>0.05)。结论 除热滋阴方结合安宫黄体酮治疗阴虚内热型崩漏的临床效果显著,安全性高,值得临床推广。
Objective To explore curative effect of removing heat and nourishing yin formula combined with medroxyprogesterone(yin deficiency and internal heat type)and effect on traditional chinese medicine syndrome,E_(2),FSH,LH levels of patients.Methods The paper included 61 patients with yin deficiency and internal heat type metrorrhagia(from March 2019 to January 2021),and divided them into observation group and control group with random number table method.Control group(31 cases)was treaetd with combination of estrogen and progesterone,while observation group(30 cases)with combination of removing heat and yin nourishing formula on the basis of control group.Clinical effect between two groups was compared before and after treatment,integral changes of traditional Chinese medicine syndromes(including excessive or incomplete vaginal bleeding,restless heat of the five hearts,hot flashes,red cheekbones,dry throat and mouth,dry stools,etc.),changes in serum estradiol(E_(2)),follicle stimulating hormone(FSH),luteinizing hormone(LH)levels,blood red egg white(Hb)levels,and adverse reactions.Result Control group had lower effective rate than observation group,(P<0.05).Before treatment,traditional Chinese medicine syndrome scores(including excessive or incomplete vaginal bleeding,restless heat,hot flashes,red cheeks,dry throat and mouth,dry stools,etc.),E_(2),FSH,LH,Hb,and other indicators comparison between two groups showed(P>0.05).After treatment,TCM syndrome scores,E_(2),FSH,LH,Hb,and other indicators improved.After treatment,TCM symptoms(inclduing excessive vaginal bleeding or incomplete dripping,restlessness of the five hearts,hot flashes,redness of the cheekbones,dry throat and mouth,dry stools,etc.)scores,E_(2),FSH,LH,Hb,and other indicators in observation group were higher than than control group(P<0.05).Control group had 1 case of nausea,1 case of vomiting,and 1 case of dizziness,while observation group had 1 case of fatigue and 1 case of dizziness.Adverse reactions of patients could be self alleviated(P>0.05).Conclusion Combination of removing heat and nourishing yin formula combined with medroxyprogesterone can achieve significant clinical effect and high safety in treatment of metrorrhagia(yin deficiency and internal heat type),which is worthy of application and research.
作者
邓倩倩
刘玉静
DENG Qianqian;LIU Yujing(Department of Gynecology,Dezhou Lingcheng District Hospital of Traditional Chinese Medicine,Dezhou,Shandong 253500)
出处
《智慧健康》
2023年第20期71-75,共5页
Smart Healthcare
关键词
崩漏
阴虚内热型
除热滋阴方
安宫黄体酮
疗效
不良反应
Metrorrhagia
Yin deficiency and internal heat type
Removing heat and nourishing yin formula
Medroxyprogesterone
Efficacy
Adverse reactions
