摘要
目的:评价医院骨折前期镇痛药物的使用情况,为临床合理用药提供参考。方法:调取2021—2022年骨折前期镇痛药物使用情况的相关信息,分析用药金额、用药频度(defined daily dose system,DDDs)、日限定费用(defined daily cost,DDC)、药物利用指数(druy utilization index,DUI)。结果:2021—2022年医院骨折前期镇痛药物使用占比中,塞来昔布胶囊、艾瑞昔布片、洛索洛芬钠片、盐酸羟考酮注射液、氨酚双氢可待因片依次排前5位;氨酚双氢可待因片、塞来昔布胶囊、艾瑞昔布片、洛索洛芬钠片、盐酸曲马多缓释片的DDDs稳居前5位。盐酸羟考酮注射液的DDC最高,洛索洛芬钠片的DDC最低。塞来昔布胶囊DUI值最大,且大于1;盐酸羟考酮注射液DUI值最小。结论:医院骨折前期镇痛药物应用基本合理,但个别药物费用较高,值得关注。
Objective:To evaluate the use of analgesics in the early stage of fractures in hospitals and provide reference for rational clinical medication.Methods:Relevant information on the use of analgesic drugs in the early stage of fracture from 2021 to 2022 was collected,and the consumption sum,defined daily dose system(DDDs),defined daily cost(DDC)and druy utilization index(DUI)were analyzed.Results:The proportion of analgesic drugs used in the early stage of hospital fractures from 2021 to 2022,celecoxib capsules,irecoxib tablets,loxoprofen sodium tablets,oxycodone hydrochloride injection,and paracetamol dihydrocodeine tablets ranked the top 5 in order;the DDDs of paracetamol dihydrocodeine tablets,celecoxib capsules,irecoxib tablets,loxoprofen sodium tablets,and tramadol hydrochloride sustained-release tablets ranked top 5.The DDC of oxycodone hydrochloride injection was the highest,and that of loxoprofen sodium tablets was the lowest.Maximum DUI value of celecoxib capsules,hydroxycodone hydrochloride injection has the lowest DUI value.Conclusion:The use of analgesics in the early stage of hospital fractures is basically reasonable,but some drugs have higher costs and are worth paying attention to.
作者
周瑞华
李文霞
ZHOU Ruihua;LI Wenxia(Emergency Department of Henan Luoyang Orthopedic Hospital/Henan Orthopedic Hospital,Luoyang 471000,Henan,China)
出处
《中国药物滥用防治杂志》
CAS
2023年第11期1881-1883,共3页
Chinese Journal of Drug Abuse Prevention and Treatment
基金
河南省医学科技攻关计划项目(编号:LHGJ20191150)。