摘要
通过对古籍文献调研、中药现代研究进展及其研究成果的梳理,结合中医临床及中药学等学科领域内的专家学者的认识及应用经验,经讨论认为当归的主要功效为补血活血、调经止痛、润肠通便。主治病症为月经不调、痛经、便秘。现代药理学研究靶点为血小板聚集、低血细胞及血红蛋白。现代药理研究发现,当归及其有效成分具有抗血小板聚集及抗血栓、改善心血管、护肝、抗炎、抗肿瘤、兴奋和抑制子宫平滑肌等作用。本品无毒,但脾虚便溏者慎用。临床使用剂量为5 g~30 g。内服时应该根据不同疾病,或同一疾病的不同阶段进行使用,并积极探索当归用量与其主治病症、现代药理学研究靶点的量效关系。
Through the review of ancient books and literature, the modern research progress of Traditional Chinese medicine and its research results, combined with the knowledge and application experience of experts and scholars in the field of Chinese medicine and Chinese pharmacy, it is believed that Angelica angelica has the following effects the efficacy: replenishing blood and promoting blood circulation, regulating menstrual flow and relieving pain, moistening bowel. The targets of modern pharmacological research are platelet aggregation, low blood cells and hemoglobin. Modern pharmacological studies have found that Angelica sinensis and its active components have the effects of anti-platelet aggregation and anti-thrombus, cardiovascular improvement, liver protection, anti-inflammatory, anti-tumor, excitation and inhibition of uterine smooth muscle. This product is non-toxic, but should be used with caution in patients with spleen deficiency and loose stool. The clinical dosage is 5g~30g. When taken internally, it should be used according to different diseases or different stages of the same disease, and actively explore the dose-effect relationship between the dosage of Angelica and its main symptoms and modern pharmacological research targets.
作者
李梅
杨梅
赵琦
李开楊
汪倩
Li Mei;Yang Mei;Zhao Qi;Li Kaiyang;Wang Qian(Guizhou University of Traditional Chinese Medicine,Guiyang 550025,Guizhou,China;The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550003,Guizhou,China)
出处
《贵州中医药大学学报》
2023年第6期32-36,共5页
Journal of Guizhou University of Traditional Chinese Medicine
基金
国家自然科学基金项目,项目编号:82160866
贵州省科技计划项目,项目编号:黔科合基础-ZK[2023]一般433
贵州省卫健委科技基金,项目编号:gzwkj2023-208。
关键词
当归
月经不调
痛经
便秘
现代药理
研究靶点
用量
Angelica
Irregular menstruation
Dysmenorrhea
Constipation
Modern pharmacology
Re-search target
