摘要
目的:观察生津润目方熏蒸联合睑板腺按摩及玻璃酸钠滴眼液治疗干眼症的临床疗效。方法:选取100例干眼症患者,采用随机数字表法分为对照组和观察组各50例。2组均给予常规治疗,包括玻璃酸钠滴眼液滴眼和睑板腺按摩,对照组在常规治疗基础上加0.9%氯化钠溶液熏蒸,观察组在常规治疗基础上加生津润目方熏蒸。2组均治疗4周。比较2组治疗前后中医证候评分、睑板腺评分和干眼临床指标。结果:治疗后,2组眼部干涩隐痛、白睛红赤、久视疲劳、异物感评分较治疗前降低(P<0.05),且观察组各项评分低于对照组(P<0.05)。治疗后,2组睑板腺评分较治疗前降低(P<0.05),且观察组睑板腺评分低于对照组(P<0.05)。治疗后,2组角膜荧光染色评分(FL)较治疗前降低,泪液分泌试验(SIT)值、泪膜破裂时间(BUT)较治疗前升高(P<0.05);且观察组FL评分低于对照组,SIT值、BUT高于对照组(P<0.05)。结论:生津润目方熏蒸联合睑板腺按摩及玻璃酸钠滴眼液能够改善干眼症患者临床症状,增强睑板腺功能,提高角膜稳定性,疗效确切。
Objective:To observe the clinical effect of fumigation with Shengjin Runmu Prescription combined with meibomian gland massage and Sodium Hyaluronate Eye Drops for xerophthalmia.Methods:A total of 100 cases of patients with xerophthalmia were selected and divided into the control group and the observation group according to the random number table method,with 50 cases in each group.Both groups were given routine treatment including Sodium Hyaluronate Eye Drops and meibomian gland massage;the control group was additionally treated with fumigation with 0.9%sodium chloride solution,and the observation group was additionally treated with fumigation with Shengjin Runmu Prescription.Both groups were treated for 4 weeks.Traditional Chinese medicine syndrome scores,scores of meibomian gland,and clinical indicators of dry eye were compared between the two groups before and after treatment.Results:After treatment,the scores of dryness and dull pain in the eyes,hyperemia of the conjunctiva,visual fatigue from intense use,and foreign body sensation in the two groups were decreased when compared with those before treatment(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the scores of meibomian gland in the two groups were decreased when compared with those before treatment(P<0.05),and the score in the observation group was lower than that in the control group(P<0.05).After treatment,the scores of corneal fluorescence staining(FL)in the two groups were decreased when compared with those before treatment,and the values of Schirmer's test(SIT)and tear film break-up time(BUT)were increased(P<0.05);FL score in the observation group was lower than that in the control group,and SIT value and BUT in the observation group were higher than those in the control group(P<0.05).Conclusion:For patients with xerophthalmia,fumigation with Shengjin Runmu Prescription combined with meibomian gland massage and Sodium Hyaluronate Eye Drops can improve their clinical symptoms,the function of the meibomian gland,and corneal stability,and have a definite curative effect.
作者
胡晓玲
余丽华
包露露
HU Xiaoling;YU Lihua;BAO Lulu(Yongkang Hospital,Yongkang Zhejiang 321300,China)
出处
《新中医》
CAS
2023年第21期113-116,共4页
New Chinese Medicine
基金
永康市科技计划项目(202145)。
关键词
干眼症
生津润目方
睑板腺按摩
熏蒸
玻璃酸钠滴眼液
中医证候评分
Xerophthalmia
Shengjin Runmu Prescription
Meibomian gland massage
Fumigation
Sodium Hyaluronate Eye Drops
Traditional Chinese medicine syndrome scores
