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透析患者脑小血管病患病情况的研究现状及其机制探讨

Research status and mechanism exploration on the prevalence of cerebrovascular disease in dialysis patients
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摘要 脑小血管病(CSVD)是导致老年人认知障碍、步态异常、情感障碍和日常生活能力下降的重要原因之一。目前研究发现接受持续性透析治疗的终末期肾病患者的CSVD、认知障碍、情感障碍的发生率远高于健康人群。本综述查阅近5年相关文献,阐述透析患者CSVD研究现状,并试图探讨其发病机制,以期广大研究者和临床医师关注和重视透析患者CSVD的发病情况及其所导致的临床症状。 Cerebrovascular disease(CSVD)is one of the important causes of cognitive impairment,gait abnormalities,emotional disorders,and decreased daily living ability in elderly people.At present,it has been found that the incidence of CSVD,cognitive impairment,and emotional disorders in end-stage renal disease patients receiving continuous dialysis treatment is much higher than that of healthy individuals.This review reviews relevant literature in the past 5 years,elaborates on the current research status of CSVD in dialysis patients,and attempts to explore its pathogenesis,to attract attention from researchers and clinical physicians to the incidence and clinical symptoms of CSVD in dialysis patients.
作者 白明悦 杨淑娜 胡红梅 胡文立 Bai Mingyue;Yang Shuna;Hu Hongmei;Hu Wenli(Department of Neurology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)
出处 《中华脑血管病杂志(电子版)》 2023年第5期505-509,共5页 Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
基金 国家自然科学基金项目(82001244)。
关键词 终末期肾病 透析 脑小血管病 End stage renal disease Dialysis Cerebrovascular disease
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