摘要
目的 近年来老年性消化性溃疡发病率逐年上升,对于消化性溃疡伴Hp感染的患者,根除Hp能提高其治愈率,探讨中西医结合治疗该病的疗效。方法 选取西双版纳傣族自治州人民医院全科门诊、河北省中医院脾胃病科门诊2020年1月—2021年12月经胃镜、14C或13C尿素呼气试验确诊消化性溃疡伴幽门螺杆菌(Helicobacter pylori, Hp)感染的老年患者60例,随机分成2组。对照组30例给予雷贝拉唑联合阿莫西林、克拉霉素、铋剂四联杀菌治疗,观察组30例采用中西医结合治疗,4周后进行疗效对比。结果 观察组症状改善均优于对照组,观察组总有效率优于对照组(P<0.05)。8周后,2组根除率比较,差异无统计学意义(P>0.05)。结论 中西医结合辨证治疗老年性消化性溃疡治愈率高,但Hp转阴率差异无统计学意义。
Objective In recent years,the incidence of peptic ulcer in the elderly has been increasing year by year.For peptic ulcer patients with Hp infection,eradication of Hp can improve the cure rate,to explore the curative effect of integrated traditional Chinese and Western medicine in the treatment of the disease.Methods From January 2020 to December 2021,60 elderly patients diagnosed with peptic ulcer with Helicobacter pylori(Hp)infection by gastroscopy and 14C or 13C urea breath test were selected from the general practice clinic of Xishuangbanna Dai Autonomous Prefecture People’s Hospital and Hebei Hospital of Traditional Chinese Medicine.They were randomly divided into two groups.30 cases in control group were treated with rabeprazole combined with amoxicillin,clarithromycin and bismuth quadruple bactericidal treatment,and 30 cases in observation group were treated with integrated traditional Chinese and Western medicine.The curative effect was compared after 4 weeks.Results The improvement of symptoms in observation group was better than that in control group.The total effective rate of the observation group was better than that of the control group(P<0.05).After 8 weeks,there was no significant difference in the eradication rate between the two groups(P>0.05).Conclusion The cure rate of senile peptic ulcer treated by integrated traditional Chinese and Western medicine is high,but there is no statistical difference in Hp conversion rate.
作者
聂晶晶
董笑一
郭旭瑾
武海娜
陈芳
王骁
NIE Jingjing;DONG Xiaoyi;GUO Xujin;WU Haina;CHEN Fang;WANG Xiao(Department of Rehabilitation Medicine,Xishuangbanna Dai Autonomous Prefecture People’s Hospital,Yunnan Province,Jinghong 666100,China;Department of Gastroenterology,The First Affiliated Hospital of Hebei University of Chinese Medicine,Hebei Province,Shijiazhuang 050000,China;Department of Oncology,The First Affiliated Hospital of Hebei University of Chinese Medicine,Hebei Province,Shijiazhuang 050000,China)
出处
《光明中医》
2023年第22期4447-4449,4510,共4页
GUANGMING JOURNAL OF CHINESE MEDICINE
基金
河北省中医药管理局科研计划项目(No.2020054)
河北省财政厅老年病防治计划项目(No.2018135810)。
关键词
胃痛
老年性消化性溃疡
柴胡疏肝散
老年病
中西医结合疗法
stomachache
senile peptic ulcer
Chaihu Shugan powder
senile diseases
therapy of integrated traditional Chinese and Western medicine
