摘要
目的调查某院普外科患者围手术期预防性应用抗菌药物现况,分析潜在的问题,为今后更合理地用药提供参考。方法由医院信息系统中调取2020年5月至2023年5月1321例普外科手术患者的病历,对抗菌药物应用情况予以汇总分析。结果1321例患者中,有1193例应用抗菌药物对感染予以预防,应用率为90.31%,其中Ⅰ类切口应用率为64.96%,Ⅱ类、Ⅲ类切口应用率均达到100%;Ⅰ类切口主要采用单药给药方式,构成比为68.54%,Ⅱ类、Ⅲ类切口均主要采用两种药物联合的给药方式,构成比为56.42%、81.98%;Ⅰ类切口给药时间不合理共16例,均表现为术前>2 h给药;Ⅱ类切口给药时间不合理共169例,其中术前>2 h给药108例,术后给药至拆线61例;Ⅲ类切口给药时间不合理共115例,其中术前>2 h给药41例,术后给药至拆线74例;普外科患者抗菌药物使用总频次为2043次,使用频次最多的抗菌药物为第二代头孢菌素,使用频率为42.49%(868/2043),主要为头孢呋辛钠,使用频率为39.75%(812/2043),其次为第三代头孢占菌素,具体药物为头孢噻肟钠,使用频率为18.80%。结论本院普外科患者围手术期预防性应用抗菌药物种类基本符合原则,但在联合给药、给药时间方面存在一定不合理之处,尚需加强对此类药物预防性应用规范度的管理。
Objective To investigate the current status of perioperative prophylactic use of antibiotics in general surgical patients in a certain hospital,analyze potential problems,and provide reference for more rational drug use in the future.Methods The medical records of 1321 patients in general surgery from May 2020 to May 2023 were retrieved from the hospital information system,and the use of antibiotics was summarized and analyzed.Results Out of 1321 patients,1193 were treated with antibiotics to prevent infection,with an application rate of 90.31%,the application rate of class I incisions was 64.96%,and the application rates of class II and III incisions reached 100%;class I incisions mainly use single drug administration,with a composition ratio of 68.54%,class II and III incisions mainly use a combination of two drugs,with a composition ratio of 56.42%and 81.98%;16 cases had unreasonable administration time in class I incision,all of which were of administration>2 hours before surgery;169 cases had unreasonable administration time in class II incision,of which 108 cases were of administration>2 hours before surgery,and 61 cases were of postoperative medication until suture removal;115 cases had unreasonable administration time in class III incision,of which 41 cases were of administration>2 hours before surgery,and 74 cases were of postoperative medication until suture removal;the total frequency of antibiotic use in general surgical patients was 2043,and the most frequently used antibiotic was the second-generation cephalosporin,with a frequency of 42.49%(868/2043),mainly cefuroxime sodium,with a usage frequency of 39.75%(812/2043),the next was the third-generation cephalosporin,specifically cefotaxime sodium,with a usage frequency of 18.80%(384/2043).Conclusion The types of prophylactic use of antibiotics in the perioperative period of general surgical patients in our hospital are basically in line with the principles,but there are certain unreasonable aspects in the combination administration and administration time.It is still necessary to strengthen the management of standardized prophylactic use of such drugs.
作者
赵滨涵
唐城
ZHAO Binhan;TANG Cheng(The Third Surgical Department,Jinxian County People,s Hospital,Nanchang,Jiangxi,331700,China;Department of General Surgery,The First Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,331700)
出处
《中国病原生物学杂志》
CSCD
北大核心
2023年第12期1430-1433,共4页
Journal of Pathogen Biology
关键词
普外科
预防使用
围术期
抗菌药物
general surgery
prophylactic use
perioperative period
antibacterial drugs
