摘要
目的:探讨黄芪及其复方治疗肾病综合征的研究热点和发展趋势。方法:检索中国知网(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)黄芪及其复方治疗肾病综合征的中文文献,时间范围为1990年01月01日—2021年12月31日,所得文献用NoteExpress软件查重再进行人工筛选排除后,运用citeSpace6.1R2软件分别对文献的作者和关键词绘制成图谱,并进行可视化分析。结果:共纳入中文文献383篇,涉及560位相关作者,作者合作团队主要以王海燕、叶红、康国贵为代表。关键词分析中高频关键词有“原发性肾病综合征”、“黄芪注射液”、“防己黄芪汤”、“临床观察”等,关键词聚类分析中得到13个聚类,关键词突现分析中得到20个突现词。结论:发文量整体处于增长趋势,但作者间合作较为分散。研究热点主要集中在治疗肾病综合征的主要类型、复方治疗及作用机制。未来发展趋势由临床观察、临床疗效向基于网络药理学、数据挖掘、Meta分析治疗肾病综合征方面转变。
Objective:To explore the research hotspot and development trend of Astragalus and its compound in the treatment of nephrotic syndrome.Methods:The Chinese literatures of Astragalus membranaceus and its compound treatment for nephrotic syndrome were retrieved from CNKI,Wanfang Data and VIP.The time range was from January 1,1990 to December 31,2021.The obtained literatures were checked by NoteExpress software and manually screened and excluded.CiteSpace6.1R2 software was used to map the authors and keywords of the literature,and the visualization analysis was carried out.Results:A total of 383 Chinese literatures were included,involving 560 relevant authors.The authors were mainly represented by Wang Haiyan,Ye Hong and Kang Guogui.In the keyword analysis,the high-frequency keywords included“primary nephrotic syndrome”,“Huangqi injection”,“Fangji Huangqi decoction”,“clinical observation”,etc.Thirteen clusters were obtained in the keyword cluster analysis,and 20 emergent words were obtained in the keyword outburst analysis.Conclusion:The number of published papers is on the increase,but the cooperation among authors is scattered.The research hotspots mainly focus on the main types of treatment of nephrotic syndrome,compound therapy and mechanism of action.The future development trend is changing from clinical observation and clinical efficacy to the treatment of nephrotic syndrome based on network pharmacology,data mining and meta-analysis.
作者
陈宜瑶
杨育同
冯玉华
CHEN Yiyao;YANG Yutong;FENG Yuhua(Shanxi University of Chinese Medicine,Jinzhong,030000;不详)
出处
《中国中西医结合肾病杂志》
2023年第10期867-870,I0003,共5页
Chinese Journal of Integrated Traditional and Western Nephrology
基金
山西省高等学校教学改革创新项目(No.J20220748)
第五批全国中医临床优秀人才研修项目(No.国中医药人教函[2022]239号)
山西省级名中医传承工作室建设项目(No.SXSMZYGZS173)
山西中医药大学校级科研项目(No.2022PY-TH-34)
山西省中医药管理局科研项目(No.2023ZYYC056,2022ZYYC265)。
