摘要
目的分析刺络拔罐联合熏灸治疗局限性神经性皮炎的效果。方法抽取2021年1月至2022年12月开封市人民医院皮肤科门诊治疗的局限性神经性皮炎患者60例,按照随机数字表法分为对照组和观察组,每组30例。对照组采用卤米松乳膏治疗,观察组采用刺络拔罐联合熏灸治疗。比较两组治疗效果、临床症状(瘙痒程度、皮损面积、皮损程度、苔藓化程度)积分、炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)]水平、不良反应发生率及复发率。结果观察组总有效率(96.67%,29/30)高于对照组(70.00%,21/30),P<0.05。治疗后,观察组瘙痒程度、皮损面积、皮损程度、苔藓化程度评分均低于对照组(P均<0.05);治疗后,观察组TNF-α、IL-6、IL-1β水平低于对照组(P<0.05)。观察组不良反应发生率(3.33%,1/30)低于对照组(26.67%,8/30),P<0.05。治疗后3、6个月,观察组复发率(3.33%,1/30;6.67%,2/30)均低于对照组(26.67%,8/30;33.33%,10/30),P均<0.05。结论刺络拔罐联合熏灸治疗局限性神经性皮炎效果显著,能快速改善患者瘙痒、皮损等症状,减轻机体炎症,降低不良反应发生率和复发率。
ObjectiveTo analyze therapeutic effect of pricking and cupping combined with fumigation and moxibustion on localized neurodermatitis.MethodsSixty patients with localized neurodermatitis treated in Outpatient Department of Dermatology in Kaifeng People’s Hospital from January 2021 to December 2022 were selected,and they were divided into control group and observation group according to random number table method,with 30 cases in each group.The control group was treated with halometasone cream,and the observation group was treated by pricking and cupping combined with fumigation and moxibustion.The efficacy,clinical symptom score(pruritus degree,lesion area,lesion degree,lichenization degree),levels of inflammatory factors,including tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and interleukin-1β(IL-1β),incidence of adverse reactions and recurrence rate were compared between the two groups.ResultsThe total effective rate of the observation group(96.67%,29/30)was higher than that of the control group(70.00%,21/30),P<0.05.After treatment,the scores of pruritus degree,lesion area,lesion degree,lichenization degree in the observation group were lower than those in the control group(all P<0.05).After treatment,the levels of TNF-α,IL-6 and IL-1βin the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions in the observation group(3.33%,1/30)was lower than that in the control group(26.67%,8/30),P<0.05.The recurrence rates of the observation group after 3 and 6 months of treatment were 3.33%(1/30)and 6.67%(2/30),which were lower than the 26.67%(8/30)and 33.33%(10/30)of the control group(all P<0.05).ConclusionsPricking and cupping combined with fumigation and moxibustion is effective in the treatment of localized neurodermatitis,which can quickly improve the symptoms of pruritus and skin lesions,alleviate the body inflammation,and reduce the incidence of adverse reactions and recurrence rate.
作者
任雷生
耿庆娜
王金娜
王哲新
Ren Leisheng;Geng Qingna;Wang Jinna;Wang Zhexin(Department of Dermatology,Kaifeng People’s Hospital,Kaifeng 475000,China)
出处
《中国实用医刊》
2023年第20期112-115,共4页
Chinese Journal of Practical Medicine
关键词
神经性皮炎
刺络拔罐
熏灸
Neurodermatitis
Pricking and cupping
Fumigation and moxibustion
