摘要
阿尔茨海默病(AD)是一种常见的年龄依赖性神经退行性疾病。中医学认为,肠道菌群和脑肠轴类似于脾胃及脑与脾胃间的关系。对于脾胃气机不畅的问题,辛开苦降法是一种行之有效的疗法。本文以分析肠道菌群、脑肠轴和AD之间的联系为基础,提出运用辛开苦降法来治疗AD的新思路,旨在为临床AD治疗带来新的观点和方法。
Alzheimer's disease(AD)is a common age-dependent neurodegenerative disease.Traditional Chinese medicine(TCM)believes that the relationship between gut flora and brain-gut axis is similar to the relationship between the spleen-stomach and the brain-spleen-stomach.Pungent dispersing and bitter descending method is an effective treatment method for inhibited spleen-stomach qi movement.Based on the analysis of the relationship between intestinal microflora,brain-gut axis and AD,the authors put forward pungent dispersing and bitter descending method for the treatment of AD,hoping to provide new idea and method for clinical treatment for AD.
作者
王帅哲
王佳伟
魏本君
WANG Shuaizhe;WANG Jiawei;WEI Benjun(Gansu University of Chinese Medicine,Lanzhou 730000,China;Key Laboratory of Dunhuang Medicine and Transformation,Ministry of Education,Lanzhou 730000,China;Key Laboratory of Excavation and Innovation and Transformation of Traditional Chinese Medicine Formulae in Gansu Province,Lanzhou 730000,China)
出处
《中医药学报》
CAS
2023年第12期10-14,共5页
Acta Chinese Medicine and Pharmacology
基金
甘肃省自然科学基金(20JR5RA180)
甘肃中医药大学引进人才项目(2018YJRC-06)
甘肃中医药大学甘肃省中医方药挖掘与创新转化重点实验室开放基金(zyzx-2020-11)
敦煌医学与转化教育部重点实验室开放基金(DHYX17-02)。
关键词
阿尔茨海默病
肠道菌群
脑肠轴
辛开苦降法
Alzheimer's disease
Intestinal flora
Brain-gut axis
Pungent dispersing and bitter descending method
