摘要
目的探讨瑞芬太尼联合丙泊酚对老年甲状腺癌根治术患者的影响。方法将100例行甲状腺癌根治术的老年患者根据麻醉方式的不同分为对照组(n=50)和观察组(n=50)。对照组患者采取七氟醚联合丙泊酚麻醉维持,观察组患者采取瑞芬太尼联合丙泊酚麻醉维持。比较两组患者术后苏醒情况、疼痛程度、血流动力学指标以及不良反应发生情况。结果观察组患者置管至拔管时间、睁眼时间、自主呼吸恢复时间均明显短于对照组,差异均有统计学意义(P﹤0.01)。术后0.5、1、3、12 h,观察组患者视觉模拟评分法(VAS)评分均低于对照组,差异均有统计学意义(P﹤0.05)。气管插管时(T_(1))、分离甲状腺时(T_(2))、术毕时(T_(3)),对照组患者收缩压(SBP)、舒张压(DBP)、心率(HR)均高于麻醉前(T0)和观察组,差异均有统计学意义(P﹤0.05)。观察组患者不良反应总发生率低于对照组,差异有统计学意义(P﹤0.05)。结论瑞芬太尼联合丙泊酚应用于老年甲状腺癌根治术患者,能够稳定患者血流动力学,减轻患者疼痛,缩短术后苏醒时间,并降低不良反应发生率。
Objective To investigate the effect of remifentanil combined with propofol on elderly patients undergoing radical thyroid cancer surgery.Method A total of 100 elderly patients who underwent radical thyroid cancer surgery were divided into control group(n=50)and observation group(n=50)according to different anesthesia methods.Patients in the control group were maintained under anesthesia with sevoflurane combined with propofol,and patients in the observation group were maintained under anesthesia with remifentanil combined with propofol.The postoperative recovery status,pain level,hemodynamic indicators,and occurrence of adverse events were compared between the two groups.Result The time from intubation to extubation,eye-opening time,and spontaneous breathing recovery time in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.01).At 0.5,1,3,12 hours after the surgery,the visual analogue scale(VAS)scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).At the time of tracheal intubation(T_(1)),when the thyroid was isolated(T_(2)),and at the end of the operation(T_(3)),the systolic blood pressure(SBP),diastolic blood pressure(DBP),and heart rate(HR)of the control group were higher than those before anesthesia(T0)and the observation group,and the differences were statistically significant(P<0.05).The total incidence of adverse events in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of remifentanil combined with propofol in elder patients undergoing radical thyroid cancer surgery could stabilize the patients’hemodynamics,reduce the patients’pain,shorten the postoperative recovery time,and reduce the incidence of adverse events.
作者
张敬伟
韩翀
ZHANG Jingwei;HAN Chong(Department of Anesthesiology and Perioperative Medicine,the Third People’s Hospital of Shangqiu,Shangqiu 476000,He’nan,China;Department of Anesthesiology,the Third People’s Hospital of Shangqiu,Shangqiu 476000,He’nan,China)
出处
《癌症进展》
2023年第20期2290-2293,共4页
Oncology Progress
关键词
甲状腺癌
瑞芬太尼
丙泊酚
七氟醚
thyroid cancer
remifentanil
propofol
sevoflurane
