摘要
目的建立钛-变色酸络合物测定防晒霜中二氧化钛方法。方法比较干灰化法、湿法消解、微波消解3种方法对样品进行预处理,采用钛-变色酸络合物比色法测定,绘制标准曲线,计算钛元素含量,并对方法稳定性、精密度及回收率进行考察。结果通过硝酸-氢氟酸-过氧化氢混合酸微波消解防晒霜样品,选择460 nm为测定波长,二氧化钛在0.0~1.0μg/mL质量浓度范围内线性关系良好,标准曲线方程为y=0.2476x+0.0281,r=0.9993,检出限为0.75 mg/kg,回收率在98.8%~103.2%,相对标准偏差(RSD)为0.96%~2.13%。结论该方法灵敏度、准确度较高,检出限低且线性范围宽,适用于防晒霜中过量添加二氧化钛的检测。
Objective To develop a titanium-chromotropic acid complex colorimetry for determination of titanium dioxide in sun-screen cream.Methods The samples were pretreated with dry ashing,wet digestion and microwave digestion,and determined using the titanium-chromotropic acid complex colorimetry.The standard curve was plotted,and the titanium content was measured.In addition,the stability,precision and recovery of the titanium-chromotropic acid complex colorimetry were evaluated.Results The sunscreen cream samples were subjected to microwave digestion with a mixture of nitric acid,hydrofluoric acid and hydrogen peroxide at a wave-length of 460 nm.Titanium dioxide showed a good linear relationship at mass concentrations of 0.0 to 1.0μg/mL,and the standard curve equation was y=0.2476x+0.0281(r=0.9993).The titanium-chromotropic acid complex colorimetry had a 0.75 mg/kg limit of detection,recovery rates of 98.8%to 103.2%and relative standard deviations of 0.96%to 2.13%.Conclusions The developed tita-nium-chromotropic acid complex colorimetry is sensitive,accurate,low in limit of detection and wide in linear range,which is suitable for determination of excessive titanium dioxide addition in titanium dioxide.
作者
陈峰
于文斌
张璐璐
杨梅桂
范小飞
CHEN Feng;YU Wen-bin;ZHANG Lu-lu;YANG Mei-gui;FAN Xiao-fei(Nantong Municipal Center for Disease Control and Prevention,Nantong,Jiangsu 226007,China;不详)
出处
《江苏预防医学》
CAS
2023年第5期550-553,共4页
Jiangsu Journal of Preventive Medicine
关键词
钛-变色酸
络合物
防晒霜
二氧化钛
Titanium-chromotropic acid
Complex
Sunscreen cream
Titanium dioxide
