摘要
目的:观察热敏灸联合益气养阴汤治疗肺癌癌因性疲乏的临床疗效。方法:选取2020年6月至2022年6月都昌县中医院肿瘤科诊断为肺癌癌因性疲乏患者60例,按照随机数字表法分为联合组和对照组,每组30例。对照组给予益气养阴汤治疗,联合组在对照组治疗的基础上加用热敏灸治疗。观察两组治疗前后癌因性疲乏量表(cancer fatigue scale, CFS)评分、中医证候积分、匹兹堡睡眠质量指数(pittsburgh sleep quality index, PSQI)、癌症患者生活质量量表(EORTCQLQ-C30)评分、免疫功能(CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+))、营养状况[白蛋白(albumin, ALB)、血红蛋白(hemoglobin, HGB)、前白蛋白(prealbumin, PA)]变化情况。结果:联合组治疗后CFS评分、中医证候积分低于对照组,差异有统计学意义(P<0.05);联合组治疗后癌症患者生活质量量表(EORTCQLQ-C30)评分高于对照组,PSQI评分低于对照组,差异有统计学意义(P<0.05);联合组治疗后CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平高于对照组,差异有统计学意义(P<0.05);联合组治疗后HGB、ALB、PA水平高于对照组,差异有统计学意义(P<0.05)。结论:热敏灸联合益气养阴汤治疗肺癌癌因性疲乏,可有效缓解癌因性疲乏患者症状,改善患者营养状态及免疫功能,提高生活质量及睡眠质量。
Objective:To observe the clinical efficacy of heat-sensitive moxibustion combined with Qi-Replenishing and Yin-Nourishing Decoction on fatigue induced by lung cancer.Methods:A total of 60 patients with fatigue induced by lung cancer diagnosed in the Department of Oncology of Duchang County Hospital of Traditional Chinese Medicine from June 2020 to June 2022 were selected and divided into the combined group and the control group according to the random number table method,with 30 cases in each group.The control group was given Qi-Replenishing and Yin-Nourishing Decoction for treatment,while the combined group was given heat-sensitive moxibustion on the basis of the treatment of the control group.The changes in cancer fatigue scale(CFS)score,TCM syndrome scores,Pittsburgh sleep quality index(PSQI),EORTCQLQ-C30 score,immune function(CD3~+,CD4~+,CD4~+/CD8~+),nutritional status[including albumin(ALB),hemoglobin(HGB),prealbumin(PA)]of the two groups before and after treatment were observed.Results:After treatment,the CFS score and TCM syndrome scores of the combined group were lower than those of the control group,and the differences were statistically significant(P<0.05);the EORTCQLQ-C30 score of the combined group was higher than that of the control group,while the PSQI score was lower than that of the control group,and all the differences were statistically significant(P<0.05);The levels of CD3~+,CD4~+,CD4~+/CD8~+in the combined group were higher than those in the control group,and all the differences were statistically significant(P<0.05);the levels of HGB,ALB,PA in the combined group were higher than those in the control group,and all the differences were statistically significant(P<0.05).Conclusion:Heat-sensitive moxibustion combined with Qi-Replenishing and Yin-Nourishing Decoction in the treatment of fatigue induced by lung cancer can effectively relieve the symptoms of cancer-induced fatigue,improve the nutritional status and immune function of patients,and improve their quality of life and sleep quality.
作者
胡玉锋
程建才
卢伊
黄松华
高翔龙
李广泉
HU Yufeng;CHENG Jiancai;LU Yi;HUANG Songhua;GAO Xiangong;LI Guangquan(Duchang County Hospital of Traditional Chinese Medicine,Duchang,Jiangxi,China,332600)
出处
《河南中医》
2023年第12期1910-1914,共5页
Henan Traditional Chinese Medicine
基金
江西省中医药管理局科技计划项目(2021A190)。
关键词
癌因性疲乏
肺癌
热敏灸
益气养阴汤
免疫功能
cancer-induced fatigue
lung cancer
heat-sensitive moxibustion
Qi-Replenishing and Yin-Nourishing Decoction
immune function
