摘要
目的比较广西不同性别及分娩孕周新生儿出生体重及胎盘重量的百分位数数值与现行标准的差别,并绘制百分位数曲线图。方法收集2019年5月至2021年12月于广西壮族自治区妇幼保健院分娩的单胎妊娠案例11731例。采用R软件中的广义可加模型(GAMLSS)绘制不同性别及分娩孕周的新生儿出生体重及胎盘重量百分位数曲线,明确其百分位数值,并与中国现行标准和国际参考标准进行比较。结果获得广西不同性别及分娩孕周的新生儿出生体重及胎盘重量百分位数曲线及其数值,其中男新生儿6264例,女新生儿5467例。随着孕周的增加,新生儿出生体重及胎盘重量均逐渐增加,但胎盘重量的百分位数数值上升变化较平缓。对于31~38孕周者,广西新生儿出生体重的第10百分位数(P_(10))值大于中国现行标准,而对于分娩孕周为39~41周者则小于中国现行标准;对于分娩孕周为34~37周者,广西新生儿出生体重的第90百分位数(P_(90))值大于中国现行标准,而对于分娩孕周为38~41周者则小于中国现行标准。对于分娩孕周为33~41周者,广西新生儿出生体重的P_(10)值大于国际参考标准,而P_(90)值小于国际参考标准。男胎的胎盘发育高峰早于女胎。结论广西新生儿出生体重百分位数数值与现行标准存在差异,相关量表的绘制应该采纳地方标准以避免诊断偏倚。此外,胎盘发育的动力学亦与胎儿性别有关。
Objective To compare the birth weight and placental weight percentile values of newborns with different genders and gestational weeks in Guangxi,and to compare them with the current standards and to plot the percentile curves.Methods A total of 11731 singleton pregnancies delivered in Maternity and Child Health Care Hospital of Guangxi Zhuang Autonomous Region during May 2019 and December 2021 were collected.The birth weight and placental weight percentile curves of the newborns with different genders and gestational weeks were plotted using generalized additive models for location,scale and shape(GAMLSS)package in R software,and their percentile values were specified and compared with the China′s current standard and the international reference standard.Results The birth weight and placental weight percentile curves of newborns with different genders and gestational weeks in Guangxi and their percentile values were obtained,including 6264 male newborns and 5467 female newborns.With the increase of gestational weeks,the birth weight and placental weight of the newborns increased gradually,but the percentile values of the placental weight increased gently.Compared with those in the China current standard,the 10th percentiles(P_(10))of the newborns′birth weight in Guangxi were large during 31 and 38 weeks of gestation,and were small during 39 and 41 weeks of gestation.Similarly,compared with those in the China current standard,the 90th percentiles(P_(90))of the newborns′birth weight in Guangxi were large during 34 and 37 weeks of gestation,and were small during 38 and 41 weeks of gestation.For 33 to 41 weeks of gestation,the P_(10) value of birth weight of the newborns in Guangxi was higher than that in the international reference standard,while the P_(90) value of birth weight of the newborns in Guangxi was lower than that in the international reference standard.The developmental peak of placenta in male fetuses occurred earlier than that in female fetuses.Conclusion The percentile values of the newborns′birth weight in Guangxi are different from those in the current standards.The local standards should be adopted to plot the relevant scales to avoid diagnostic bias.In addition,the kinetics of placental development are also related to fetal genders.
作者
韦红卫
缪丽梅
覃钰芹
袁培
冯宝莹
陈欢
彭振仁
潘平山
丘小霞
李剑
覃洁
WEI Hong-wei;MIAO Li-mei;QIN Yu-qin(Graduate School of Guangxi University of Chinese Medicine,Nanning 530200,China;Department of Obstetrics,Maternity and Child Health Care Hospital of Guangxi Zhuang Autonomous Region,Nanning 530002,China)
出处
《中国临床新医学》
2023年第12期1286-1292,共7页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
国家自然科学地区科学基金项目(编号:82060283)
国家“十三五”科技支撑重点专项子课题(编号:2016YFC1000102)。
