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强直性脊柱炎发病与二十四节气相关性研究

A study on the correlation between the onset of ankylosing spondylitis and the twenty-fourth festival season
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摘要 目的:分析陕西地区近19年强直性脊柱炎发病与二十四节气间的相关性,从时间医学角度为因时制宜理论提供临床依据。方法:采用回顾性研究方法对西安市第五医院2002年2月4日至2020年2月3日收治的12645例强直性脊柱炎住院患者的病历资料进行分析,应用圆形统计分析确定其发病高峰节气及相对高峰期。结果:2002-2020年陕西地区强直性脊柱炎患者的在发病节气上具有集中趋势(Z=47.73,P<0.05),大暑(8月5日)是发病的高峰节气,相对高峰期为春分到大雪(3月21日至12月20日)。结论:强直性脊柱炎虽不是季节性流行病,但是其发病与气候、环境及二十四节气的变化有一定的影响,陕西地区强直性脊柱炎的发病节气具有一定的集中趋势,大暑前后是发病高峰期,提示应注意该节气期间疾病的预防和早期治疗。 Objective:To analyze the correlation between the incidence of ankylosing spondylitis and the twenty-four seasons in Shaanxi region in the past 19 years,and to provide a clinical basis for the theory of seasonal adaptation from the perspective of chronomedicine.Methods:The medical records of 12645 ankylosing spondylitis inpatients admitted to the Fifth Hospital of Xi’an City from February 4,2002 to February 3,2020 were analyzed using retrospective research methods,and circular statistical analysis was applied to determine the peak seasons of incidence and the relative peak periods.Results:From 2002 to 2020,patients with ankylosing spondylitis in Shaanxi had a tendency to concentrate on the onset of the disease(Z=47.73,P<0.05),with the peak season of onset being the Great Summer(August 5)and the relative peak period being from the vernal equinox to the Great Snow(March 21-December 20),which was the most common time for the onset of the disease.Conclusion:Although ankylosing spondylitis is not a seasonal epidemic,its onset has a certain influence on the climate,environment and the changes of the 24 solar terms.The onset of ankylosing spondylitis in Shaanxi has a certain tendency to be centralized in terms of solar terms,and the peak period of the onset of the disease is before and after the Great Summer,suggesting that attention should be paid to the prevention of the disease and the early treatment of the disease during the period of the solar term.
作者 吴智龙 殷继超 胡兴律 刘英纯 刘诗若 李霖 赵宇 WU Zhilong;YIN Jichao;HU Xinglv;LIU Yingchun;LIU Shiruo;LI Lin;ZHAO Yu(Shaanxi University of Chinese Medicine,Xianyang 712046,China)
出处 《陕西中医》 CAS 2024年第1期75-79,共5页 Shaanxi Journal of Traditional Chinese Medicine
基金 陕西省重点研发计划项目(2023-YBSF-158,2022SF-173,2021SF-372) 西安市科技计划项目[20YXYJ0003(6)]。
关键词 强直性脊柱炎 圆形统计分析 二十四节气 气候 因时制宜 发病季节 Ankylosing spondylitis Circular statistical analysis Twenty-four solar terms Climate Right crop for right time Season of onset
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