摘要
目的探讨对重症糖尿病酮症酸中毒患者给予临床急诊急救治疗后获得临床效果。方法选取2020年2月—2022年4月栖霞市人民医院急诊科收治的80例重症糖尿病酮症酸中毒患者为研究对象,根据投掷硬币法分为两组,各40例。两组患者均采用基础疗法治疗,在此基础上,参照组选择常规处理+胰岛素静脉滴注抢救方法完成治疗;研究组(在常规以及参照组基础上,给予持续皮下胰岛素注射治疗。对比两组治疗总有效率、尿酮体转阴时间、酸中毒纠正时间、住院时间、血糖水平(空腹血糖、糖化血红蛋白以及餐后2 h血糖)、低血糖发生率。结果研究组治疗总有效率高于参照组,差异有统计学意义(P<0.05)。与参照组尿酮体转阴时间、酸中毒纠正时间、住院时间比较,研究组均明显缩短,差异有统计学意义(P<0.05)。治疗后,与参照组空腹血糖、糖化血红蛋白以及餐后2 h血糖比较,研究组均更低,差异有统计学意义(P<0.05)。与研究组低血糖发生率低于参照组,差异有统计学意义(P<0.05)。结论临床对重症糖尿病酮症酸中毒患者在给予常规临床急诊急救治疗的基础上,应用持续皮下胰岛素注射治疗方式,可有效提升患者疗效,缩短尿酮体转阴时间、酸中毒纠正时间、住院时间,降低血糖水平以以及低血糖发生率。
Objective To explore the clinical effects of clinical emergency first aid treatment for patients with severe diabetic ketoacidosis.Methods A total of 80 patients with severe diabetic ketoacidosis admitted to the Emergency De-partment of Qixia People's Hospital from February 2020 to April 2022 were selected as the study objects,and they were divided into two groups with 40 cases in each group according to the coin toss method.The patients in both groups were treated with basic therapy,and on this basis,the reference group chose conventional treatment+intrave-nous insulin infusion rescue method to complete the treatment.Study group(on a routine and reference basis,continu-ous subcutaneous insulin injection.The total effective rate,urine ketone conversion time,acidosis correction time,hos-pital stay,blood glucose level(fasting blood glucose,glycosylated hemoglobin,and 2-hour postprandial blood glucose)and hypoglycemia incidence were compared between the two groups.Results The total effective rate of treatment in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).Compared with the control group,the time of urine ketone conversion to negative,the time of acidosis correction and the length of hospital stay were significantly shortened in the study group,and the difference was statistically signifi-cant(P<0.05).After treatment,the fasting blood glucose,glycosylated hemoglobin and 2-hour postprandial blood glu-cose were lower than those in the control group,and the difference was statistically significant(P<0.05).The inci-dence of hypoglycemia was significantly lower than that in the study group(P<0.05).Conclusion In clinical practice,on the basis of routine clinical emergency treatment for patients with severe diabetic ketoacidosis,continuous subcuta-neous insulin injection can effectively improve the efficacy of patients,shorten the time of urine ketone conversion,acidosis correction time,hospital stay,reduce blood glucose level and the incidence of hypoglycemia.
作者
李学起
闫荟如
LI Xueqi;YAN Huiru(Department of Emergency Medicine,Qixia People's Hospital,Qixia,Shandong Province,265300 China;Depart-ment of Neurology,Qixia People's Hospital,Qixia,Shandong Province,265300 China)
出处
《糖尿病新世界》
2023年第21期182-185,共4页
Diabetes New World Magazine
关键词
重症糖尿病酮症酸中毒
临床急诊急救
血糖水平
低血糖
Severe diabetic ketoacidosis
Clinical emergency first aid
Blood glucose level
Hypoglycemia
