摘要
目的探讨轻断食对T2DM合并超重/肥胖患者血糖控制的影响。方法选取2020年4月至2021年9月于我院内分泌科治疗的T2DM合并超重/肥胖患者46例,分为对照组(Con,n=22)和轻断食组(IF,n=24),Con组予以常规诊疗,IF组通过代餐、自然饮食相结合的方式实施轻断食,同时断食日减少降糖药物。结果与Con组比较,IF组体重、BMI、降糖药物效果评分、WC、脂肪指数、臀围、内脏脂肪(VF)降幅明显(P<0.05)。干预后IF组近似T2DM缓解率高于Con组(P<0.05)。结论轻断食可减少T2DM合并超重/肥胖患者降糖药物,可能与减重、减少VF相关。
Objective To explore the effect of intermittent fasting on blood glucose control in patients with type 2 diabetes mellitus(T2DM)complicated by overweight and obesity.Methods 46 T2DM patients with overweight and obesity were divided into control group(Con,n=22)and intermittent fasting group(IF,n=24)according to their wishes.Con group was given routine diet and drug treatment by specialists in endocrinology.IF group completed the intermittent fasting by using a combination of meal replacement and natural diet,and hypoglycemic drugs were reduced on fasting days.Results Compared with Con group,IF group showed a significant decrease in body weight,BMI,hypoglycemic drug efficacy score,WC,fat index,hip circumference and visceral fat(VF)(P<0.05).After intervention,the proportion of diabetes in remission or near remission in IF group was higher than that in Con group(P<0.05).Conclusion Intermittent fasting can reduce the application of hypoglycemic drugs in T2DM patients with overweight and obesity,and can also reduce weight and VF.
作者
周淑晶
黄薇
闫慧娴
ZHOU Shujing;HUANG Wei;YAN Huirian(Department of Endocrinology,Beijing Haidian Hospital,Beijing 100080,China)
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2023年第12期925-928,共4页
Chinese Journal of Diabetes
基金
北京市海淀医院2020年院级科研基金项目(KYQ2020004)。
关键词
轻断食
糖尿病
2型
超重
肥胖
内脏脂肪
Intermittent fasting
Diabetes mellitus
type 2
Overweight
Obesity
Visceral fat
