摘要
目的:研究胸腹腔镜根治术联合早期肠内营养支持治疗老年食管癌的效果。方法:研究对象选取2018年01月至2021年12月我院收治的96例老年食管癌患者,按照随机数字法分为观察组和对照组,每组各48例。对照组术后采取肠外营养支持治疗,观察组术后采取肠内营养支持治疗,比较两组患者术后住院时间、肛门排气时间、首次排便时间、下床活动时间、恢复饮食时,以及术前及术后7 d的营养相关状况指标白蛋白(ALB)、总蛋白(TP)、前白蛋白(PA)和体质量指数(BMI),免疫功能相关指标CD3^(+)、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+),观察两组主要并发症的发生情况。结果:观察组住院时间、肛门排气时间、首次排便时间、恢复饮食时间均少于对照组(P<0.05);观察组术后7 d的ALB、TP、PA、BMI均高于对照组(P<0.05);观察组术后7 d的CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)均高于对照组(P<0.05);观察组吻合口瘘、肺部并发症及总并发症的发生率(P<0.05),均低于对照组。结论:早期肠内营养支持可以有效改善老年患者在胸腹腔镜联合食管癌根治术后营养状态,增强免疫功能,减少并发症,促进术后恢复,具有较大临床价值。
Objective:To study the effect of thoracoscopic and laparoscopic radical surgery combined with early enteral nutrition support in the treatment of elderly esophageal cancer.Methods:The study subjects were 96 elderly esophageal cancer patients admitted to our hospital from January 2018 to December 2021.They were randomly divided into an observation group and a control group,with 48 patients in each group.The control group received postoperative parenteral nutrition support treatment,while the observation group received postoperative enteral nutrition support treatment.The postoperative hospitalization time,anal exhaust time,first bowel movement time,time to get out of bed,time to resume diet,as well as nutritional status indicators such as albumin(ALB),total protein(TP),prealbumin(PA),and body mass index(BMI),immune function indicators such as CD3^(+),CD4^(+),CD8^(+),CD4^(+)/CD8^(+) were compared between the two groups.The occurrence of major complications in both groups was observed.Results:The hospitalization time,anal exhaust time,first bowel movement time,and recovery time of the observation group were all shorter than those of the control group(P<0.05).The ALB,TP,PA and BMI of the observation group were higher than those of the control group 7 days after surgery(P<0.05).The CD3^(+),CD4^(+),CD4^(+)/CD8^(+) levels in the observation group were higher than those in the control group 7 days after surgery(P<0.05).The incidence of anastomotic fistula,pulmonary complications,and total complications in the observation group(P<0.05) was lower than that in the control group.Conclusion:Early enteral nutrition support can effectively improve the nutritional status of elderly patients after thoracoscopic and laparoscopic radical esophageal cancer surgery,enhance immune function,reduce complications,and promote postoperative recovery.It has significant clinical value.
作者
林杰
陈明治
高鹏飞
LIN Jie;CHEN Mingzhi;GAO Pengfei(Yixing People's Hospital,Jiangsu Yixing 214200,China)
出处
《现代肿瘤医学》
CAS
2024年第1期64-68,共5页
Journal of Modern Oncology
基金
江苏大学2022年度医教协调创新基金(编号:JDY2022016)。
关键词
胸腹腔镜根治术
早期肠内营养支持
食管癌
营养状态
吻合口瘘
laparoscopic radical thoracic surgery
early enteral nutritional support
esophageal cancer
nutritional status
anastomotic fistula
