摘要
目的探讨经筋透刺法联合穴位注射治疗顽固性面瘫的临床疗效。方法选取2020年5月至2021年10月在遂宁市中医院接受治疗的120例顽固性面瘫病人,采用随机数字表法随机分为单一组(60例)和联合组(60例),两组病人均给予常规西药治疗,单一组在此基础上给予穴位注射,联合组在此基础上给予经筋透刺法联合穴位注射,比较两组病人治疗前后面神经功能、神经生长因子(NGF)和胶质细胞源性神经营养因子(GDNF)水平、神经功能分级(H-B)评分、面瘫Portmann评分、Sunnybrook量表、复发率及临床疗效。结果单一组和联合组治疗后面神经功能明显改善,且联合组面神经功能改善情况明显优于单一组(P<0.05);单一组H-B评分治疗后较治疗前降低(2.63±0.54)分比(4.01±0.73)分,联合组(1.67±0.49)分比(4.03±0.71)分(P<0.05),且联合组H-B评分低于单一组(P<0.05),单一组和联合组GDNF(12.16±3.33)mg/L比(8.92±1.35)mg/L、(15.54±3.42)mg/L比(8.89±1.37)mg/L、NGF水平(12.16±3.33)mg/L比(8.92±1.35)mg/L、(15.54±3.42)mg/L比(8.89±1.37)mg/L、面瘫Portmann评分(15.31±1.03)分比(6.69±0.68)分、(17.24±1.16)分比(6.72±0.71)分、Sunnybrook量表评分(69.16±10.67)分比(36.42±10.17)分、(78.64±11.56)分比(36.17±10.13)分治疗后较治疗前升高,且联合组GDNF、NGF水平、面瘫Portmann评分、Sunnybrook量表评分高于单一组(P<0.05);联合组总复发率(3.33%)低于单一组(13.33%)(P<0.05);联合组总有效率(90.00%)明显高于单一组(75.00%)(P<0.05)。结论经筋透刺法联合穴位注射可改善顽固性面瘫病人临床症状及面神经功能,疗效较好且复发率较低。
Objective To investigate the clinical efficacy of the meridian tendon penetration method combined with acupoint injec⁃tion in the treatment of refractory facial paralysis.Methods From May 2020 to October 2021,120 patients with refractory facial paral⁃ysis who received treatment at Suining Hospital of Traditional Chinese Medicine were selected and randomly divided into a single group(60 cases)and a combined group(60 cases)by using a random number table method.Both groups of patients were treated with conventional Western medicines,and the single group was given acupoint injections on this basis,while the combined group was given the meridian tendon penetration method combined with acupoint injection on this basis.The nerve function,nerve growth factor(NGF)and glial cell-derived neurotrophic factor(GDNF)levels,neurological function classification(H-B)scores,Portmann score of facial pa⁃ralysis,Sunnybrook scale,recurrence rate and clinical efficacy were compared between the two groups before and after treatment.Re⁃sults The facial nerve function in the single group and the combined group was significantly improved after treatment,and the im⁃provement in facial nerve function in the combined group was significantly better than that in the single group(P<0.05).The H-B scores were lower after treatment than before treatment in the single group[(2.63±0.54)points vs.(4.01±0.73)points],and in the com⁃bined group[(1.67±0.49)points vs.(4.03±0.71)points](P<0.05),and the H-B scores in the combined group were lower than those in the single group(P<0.05).Single group and combined group GDNF[(12.16±3.33)vs.(8.92±1.35)mg/L,(15.54±3.42)vs.(8.89±1.37)mg/L],NGF levels[(12.16±3.33)vs.(8.92±1.35)mg/L(15.54±3.42)vs.(8.89±1.37)mg/L],facial paralysis Portmann score[(15.31±1.03)vs.(6.69±0.68)points,(17.24±1.16)vs.(6.72±0.71)points],Sunnybrook scale score[(69.16±10.67)vs.(36.42±10.17)points,(78.64±11.56)vs.(36.17±10.13)points]increased after treatment compared to before treatment,and levels of GDNF and NGF,facial paralysis Portmann score,and Sunnybrook scale score in the combined group were higher than those in the single group(P<0.05).The total recurrence rate of the combined group(3.33%)was lower than that of the single group(13.33%)(P<0.05)and the total effective rate of the combined group(90.00%)was significantly higher than that of the single group(75.00%)(P<0.05).Conclusion The meridian tendon penetration method combined with acupoint injection can improve the clinical symptoms and facial nerve function of patients with intractable facial paralysis,with a better curative effect and a lower recurrence rate.
作者
姬锋养
赵艳
陈志
石瑛
李爱东
JI Fengyang;ZHAO Yan;CHEN Zhi;SHI Ying;LI Aidong(Department of Acupuncture and Rehabilitation,Suining Hospital of Traditional Chinese Medicine,Suining,Sichuan 629000,China;Department of Neurology,Suining Hospital of Traditional Chinese Medicine,Suining,Sichuan 629000,China;General Department of Zhenji-angsi Community Health Service Center,Suining,Sichuan 629000,China)
出处
《安徽医药》
CAS
2024年第1期185-188,共4页
Anhui Medical and Pharmaceutical Journal
关键词
面神经麻痹
针刺穴位
经筋透刺法
穴位注射
神经生长因子
胶质细胞源性神经营养因子
Facial paralysis
Acupuncture points
Meridian tendon penetration method
Acupoint injection
Nerve growth fac⁃tor
Glial cell-derived neurotrophic factor
