摘要
诱导膜是将聚甲基丙烯酸甲酯骨水泥植入骨缺损处产生的具有促进骨骼愈合的生物膜,其内含丰富的血管、生长因子和细胞,可在诱导膜的形成及骨缺损修复重建的过程中发挥着重要作用。诱导膜可以从间隔物周围形成,也可以从骨折断端的骨膜延续而成或二者皆有,其形成机制可能与机体的修复能力和异物反应有关。诱导膜的质量会受到间隔物的性质及组成、第二阶段手术时机、骨缺损的类型及部位、患者自身条件及软组织环境等因素的影响。诱导膜技术使大段骨缺损的治疗简单化,相较于其他生物膜,其在手术操作及修复骨缺损方面均具有较大的优势。
The Inductive membrane is a biological membrane produced by implanting polymethyl methacrylate bone cement into bone defects,which promotes bone healing.It contains abundant blood vessels,growth factors,and cells,playing an important role in the formation of the inductive membrane and the process of bone defect repair and reconstruction.The inductive membrane can form around the spacer or extend from the periosteum at the fracture end or both.The formation mechanism may be related to the body’s repair capacity and foreign body reaction.The quality of the inductive membrane is affected by factors such as the nature and composition of the spacer,the timing of two-stage surgery,the type and location of the bone defect,the patient’s own conditions,and the soft tissue environment.Inductive membrane technology simplifies the treatment of large segmental bone defects,and compared with other biological membranes,it has great advantages in surgical procedures and bone defect repair.
作者
李明辉
韩涛
吕利军
牟贵生(综述)
高秋明(审校)
LI Minghui;HAN Tao;LÜLijun;MU Guisheng;GAO Qiuming(First School of Clinical Medicine,Gansu University of Chinese Medicine,Lanzhou 730030;Department of Orthopedic Trauma,940th Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army,Lanzhou 730050,China)
出处
《临床与病理杂志》
2023年第10期1872-1879,共8页
Journal of Clinical and Pathological Research
基金
甘肃省自然科学基金(21JR11RA001)
联勤保障部队第九四〇医院科研计划(2021yxky037)。
