摘要
通过对以棕榈酰五肽-4为主要功能成分化妆品的功效进行评价,研究建立人体紧致功效评价方法体系。筛选31名20~50岁女性受试者,分别在使用产品0周、4周和8周,通过客观测试数据、图像方法及受试者自我评估方法对皮肤各项指标进行评估,采集受试者脸颊、眼角部位的皮肤弹性、皮肤真皮密度等参数,以及TPEF图像及SHG图像,并进行比较分析。结果显示,8周后皮肤弹性、真皮密度(P<0.001)及真-表皮链接指数(DEJI)(P<0.01)有显著变化,与受试者自我评分结果一致,表明方法之间具有相关性。该研究方法可为建立化妆品紧致功效评价方法体系提供技术支持。
By evaluating the efficacy of a cosmetics with palmitoyl pentapeptide-4 as the main functional ingredient,the study establishes a clinical evaluation method system for firming efficacy.Thirty-one female subjects aged 20-50 were screened,and the skin indexes including the objective test data,image methods and subject self-assessment methods were evaluated after using the product for 0 week,4 weeks and 8 weeks,respectively.The parameters of skin elasticity and skin dermal density in the cheeks and canthus of the subjects,as well as the TPEF images and the SHG images,were captured,and comparative analyses were carried out.The results show significant changes in skin elasticity,dermal density(P<0.001)and DEJI(P<0.01)after 8 weeks,which are consistent with the results of the subjects’selfratings,indicating a correlation between the methods.This research can provide technical supports for the establishment of a cosmetic firming efficacy evaluation method system.
作者
马月滢
刘琦
加萌
王俊杰
王玮
赵华
Yueying Ma;Qi Liu;Meng Jia;Junjie Wang;Wei Wang;Hua Zhao(College of Light Industry Science and Engineering,Beijing Technology and Business University,Beijing 100048,China;Beijing EWISH Testing Technology Co.,Ltd.,Beijing 100142,China;College of Future Technology,Peking University,Beijing 100871,China;Beijing Transcend Vivoscope Bio-Technology Co.Ltd.,Beijing 100085,China)
出处
《日用化学工业（中英文）》
北大核心
2024年第1期73-79,共7页
China Surfactant Detergent & Cosmetics
关键词
弹性
紧致度
双光子成像技术
超声
化妆品功效评价
弹性纤维
胶原纤维
elasticity
firmness
two-photon imaging technology
ultrasound
evaluation of cosmetic efficacy
elastin fibres
collagen fibres
