摘要
目的研究经鼻插入型肠梗阻导管在治疗恶性肠梗阻(MBO)中的应用效果。方法选择我院2020年2月~2022年2月收治的120例MBO患者,以随机数字表法分为观察组60例及常规组60例,两组均开展禁食水、补液、纠正酸碱平衡以及静脉肠外营养支持等常规治疗。常规组实施普通胃管减压处理,观察组开展经鼻插入型肠梗阻导管处理。分析两组临床疗效、肠梗阻缓解情况、并发症发生情况,入院第5天、第10天的血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平的差异。结果观察组治疗总有效率高于常规组(P<0.05)。观察组引流量为(102.33±12.50)ml,多于常规组的(78.37±7.39)ml,而排气时间、腹胀腹痛减轻时间分别为(2.59±0.31)d、(3.21±0.53)d,均短于常规组的(3.71±0.44)d、(4.51±0.62)d(P<0.05)。观察组并发症发生率低于常规组(P<0.05)。入院第5天、第10天观察组的IL-6、TNF-α水平低于常规组(P<0.05)。结论经鼻插入型肠梗阻导管应用于MBO治疗中的效果较佳,可有效缓解肠梗阻症状,减少并发症的发生,降低血清炎症因子水平。
Objective To study the application effect of transnasal intestinal obstruction catheter in the treatment of malignant bowel obstruction(MBO).Methods A total of 120 patients with MBO treated in our hospital from February 2020 to February 2022 were selected and divided into observation group(60 cases)and routine group(60 cases)by random number table method.Both groups were given routine treatment such as fasting water,rehydration,correction of acid-base balance and intravenous parenteral nutrition support.Common gastric tube decompression was performed in the routine group,and transnasal intestinal obstruction catheter was performed in the observation group.The clinical efficacy,remission of intestinal obstruction,incidence of complications,serum interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)levels were analyzed between the two groups on the 5th and 10th day of admission.Results The total effective rate of treatment in the observation group was higher than that of the routine group(P<0.05).The drainage volume of the observation group was(102.33±12.50)ml,which was more than that of the routine group(78.37±7.39)ml,while the exhaust time,relief time of abdominal distension and abdominal pain were(2.59±0.31)days and(3.21±0.53)days respectively,which were shorter than that of the routine group(3.71±0.44)days and(4.51±0.62)days(P<0.05).The incidence of complications in the observation group was lower than that in the routine group(P<0.05).The levels of IL-6 and TNF-αin the observation group on the 5th and 10th day of admission were lower than those in the routine group(P<0.05).Conclusion The effect of nasal inserted intestinal obstruction catheter in MBO treatment is better.It can effectively alleviate the symptoms of intestinal obstruction,reduce the incidence of complications and reduce the level of serum inflammatory factors.
作者
周高晋
尚立清
闫军
ZHOU Gao-jin;SHANG Li-qing;YAN Jun(The Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830063,China.;不详)
出处
《医师在线》
2024年第1期36-39,共4页
Journal of Doctors Online
关键词
恶性肠梗阻
经鼻插入型肠梗阻导管
应用效果
并发症
炎症因子
Malignant bowel obstruction
Transnasal obstruction catheter
Application effect
Complications
Inflammatory factors
