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血乳酸水平与2 型糖尿病视网膜病变的相关性研究

Study on the Correlation between Blood Lactic Acid Level and Type 2 Diabetes Retinopathy
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摘要 目的探讨2型糖尿病(T2DM)患者血乳酸水平与糖尿病视网膜病变(DR)的关系。方法选择2023年2月至2023年7月我院收治的145例T2DM患者,根据病史及辅助检查结果分为伴DR组(n=60)、不伴DR组(n=85)。收集患者临床资料,分析血液生化指标及血乳酸水平与DR的关系。结果伴DR组的T2DM病程明显长于不伴DR组,血乳酸水平明显高于不伴DR组(P<0.05)。二元Logistic回归分析结果显示T2DM病程及血乳酸水平是DR的危险因素(P<0.05)。结论血乳酸水平升高是DR的危险因素。 Objective To explore the correlation between blood lactate level and diabetic retinopathy(DR)among patients with type 2 diabetes mellitus(T2DM).Methods 145 T2DM patients admitted to our hospital from February 2023 to July 2023 were selected and divided into DR group(n=60)and non-DR group(n=85)according to the medical history and auxiliary examination results.The general data of all patients were collected,and the relation of biochemical indicators and blood lactate level with diabetic retinopathy was analyzed.Results The T2DM duration of DR group was significantly longer than that of the non-DR group,and the blood lactate level was significantly higher than that of the non-DR group(P<0.05).Binary Logistic regression analysis showed that T2DM duration and serum lactate level were the risk factors for DR(P<0.05).Conclusions Elevated serum lactate level is a risk factor for DR.
作者 楚晓婧 李俊 乔焱 CHU Xiaojing;LI Jun;QIAO Yan(Department of Endocrinology,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou 450014,China)
出处 《临床医学工程》 2024年第1期123-124,共2页 Clinical Medicine & Engineering
基金 河南省医学科技攻关计划联合共建项目(LHGJ20220453)。
关键词 2型糖尿病 糖尿病视网膜病变 乳酸 Type 2 diabetes mellitus Diabetic retinopathy Lactate
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