摘要
目的:研究雷火灸联合等速结合本体感觉训练对膝关节骨性关节炎(KOA)患者股四头肌功能、血清基质金属蛋白酶(MMP)的影响。方法:选择2019年8月至2021年7月在我院接受治疗的98例KOA患者,按照随机数表法进行分组,对照组49例采用西药+等速结合本体感觉训练治疗,研究组49例采用雷火灸+等速结合本体感觉训练治疗。比较2组临床疗效、疼痛程度、病情变化情况、膝关节功能、股四头肌功能、炎症反应、血清基质金属蛋白酶(MMP-3)、MMP-9水平。结果:治疗后,研究组总有效率(95.92%)高于对照组(81.63%)(P<0.05)。治疗后,2组视觉模拟量表(VAS)、膝关节炎指数量表(WOMAC)评分、血清白介素(IL-1)、IL-6、肿瘤坏死因子(TNF-α)、MMP-3、MMP-9水平均显著降低,而Cycholm膝关节评分表(LKSS)评分、股四头肌总功量值(STW)、峰力矩值(PT)、平均功率(AP)均显著升高(P<0.05);研究组VAS、WOMAC评分、血清IL-1、IL-6、TNF-α、MMP-3、MMP-9水平低于对照组,而LKSS评分、STW、PT、AP高于对照组(P<0.05)。结论:雷火灸联合等速结合本体感觉训练治疗KOA疗效确切,可有效改善患者股四头肌功能及膝关节功能,减轻疼痛程度,促进病情好转,减轻炎症反应,调节血清MMP-3、MMP-9水平。
Objective:To study the effects of thunder fire moxibustion combined with isokinetic and proprioception training on the function of quadriceps femoris muscle and serum matrix metalloproteinases(MMP)in patients with knee osteoarthritis(KOA).Methods:A total of 98 KOA patients who received treatment in our hospital from August 2019 to July 2021 were selected and divided into groups using a random number table method.The control group(49 cases)received Western medicine combined with isokinetic proprioceptive training,and the study group(49 cases)received thunder fire moxibustion combined with isokinetic proprioceptive training.The clinical efficacy,pain degree,condition change,knee joint function,quadriceps femoris muscle function,inflammatory reaction,serum MMP-3 and MMP-9 levels were compared between the two groups.Results:The total effective rate in the study group(95.92%)was higher than that in the control group(81.63%)(P<0.05).After treatment,VAS,WOMAC scores,and serum levels of IL-1,IL-6,TNF-α,MMP-3 and MMP-9 were significantly decreased,and LKSS score,STW,PT,and AP significantly increased(P<0.05).The scores of VAS and WOMAC,and serum levels of IL-1,IL-6,TNF-α,MMP-3 and MMP-9 in the study group were lower than those in the control group,and the LKSS score,STW,PT,and AP were higher in the study group than in the control group(P<0.05).Conclusion:Thunder fire moxibustion combined with isokinetic and proprioception training has a definite therapeutic effect on KOA,which can effectively improve the function of patients’quadriceps femoris muscle and knee joint,reduce the degree of pain,promote the improvement of the condition,decrease inflammatory reaction,and regulate the levels of serum MMP-3 and MMP-9.
作者
赵红霞
李沿江
陈晓勇
陈煦
刘洪波
赵春梅
Zhao Hongxia;Li Yanjiang;Chen Xiaoyong(Department of Rehabilitation,Nan Qiao Si Ward,Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400021,China)
出处
《中国康复》
2024年第1期27-31,共5页
Chinese Journal of Rehabilitation
基金
重庆市科研机构绩效激励引导专项项目(CSTC2020JXJL130007)。
关键词
膝关节骨性关节炎
雷火灸
等速结合本体感觉训练
股四头肌功能
基质金属蛋白酶
knee osteoarthritis
thunder fire moxibustion
isokinetic combined with proprioceptive training
quadriceps femoris muscle function
matrix metalloproteinase
