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孕期女性子宫肌瘤发生因素分析及其对妊娠结局影响 被引量:3

Analysis of the factors of the uterine fibroids occurrence of pregnant women and its influence on the pregnancy outcomes
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摘要 目的:分析妊娠期女性子宫肌瘤发生及其对妊娠结局的影响.方法:选取2019年10月-2022年12月本院产科住院分娩的妊娠合并子宫肌瘤患者110例临床资料纳入观察组,同期于本院顺利分娩的正常产妇110例为对照组;收集临床资料,对行剖宫产手术的妊娠期合并子宫肌瘤患者根据具体情况选择单纯剖宫产术或剖宫产联合子宫肌瘤剔除术;统计不良分娩结局;logistic回归多因素分析影响妊娠期合并子宫肌瘤的影响因素;对比两组分娩方式和母婴妊娠结局;Spearman相关分析妊娠期发生子宫肌瘤与不良妊娠结局关系.结果:logistic回归模型分析显示,孕前体质指数高、孕前有妇科疾病和孕前1月内饮酒是妊娠期合并子宫肌瘤发生的危险因素(P<0.05);观察组不良妊娠结局发生率(60.9%)高于对照组(20.9%),剖宫产率(70.0%)高于对照组(17.3%)(均P<0.05);Spearman相关性分析显示,妊娠期发生子宫肌瘤与不良妊娠结局存在正相关性(r=0.652,P<0.05).结论:妊娠期发生子宫肌瘤影响因素包括孕前体质指数较高、孕前有妇科疾病和孕前1月内饮酒,且患者发生不良妊娠结局和剖宫产率增高,临床应加以防控. Objective:To analyze the uterine fibroids occurrenee of pregnant women.and to study its influence on the pregnancy outcomes of the women.Methods:The clinical data of 110 pregnant women with uterine fibroids(in research group)who had delivered in hospital from October 2019 to December 2022 were selected in this study.110 normal prcgnant women who had delivered in hospital during the same period were selected in control group.The clinical data of the women in the two groups were ollcted.The women in the study group were treated with simple cesarcan section or cesarean section combined with myomectomy according to the specific situation of the women.The adverse delivery outcomes of the women in the two groups were counted.Logistic regression multivariate analysis was used to analyze the influencing factors of the uterine fibroids during pregnancy.The delivery mode and the maternal and infant pregnancy outcomes were compared betwcen the two groups.Spearman correlation analysis was used to analyze the correlation between the uterine fibroids occurrence of the pregnant women and their adverse pregnancy outcomes.Results:Logistic regression analysis showed that the high pre pregnancy body mass index value,the gynecological discases before pregnancy and the drinking within 1 month before pregnancy of the women were the risk factors for their uterine fibroids occurrence during pregnancy(P<<0.05).The incidence of the adverse pregnancy outcomes(60.9%)and the cesarean section rate(70.0%)of the women in the study group were significantly higher than those(20.9%and 17.3%)of the women in the control group(all P<0.05).Spearman correlation analysis showed that the occurrence of uterine fibroids during pregnancy of the women was positively correlated with their adverse pregnancy outcomes(r=0.652,P<0.05).Conclusion:The influence factors of the uterine fibroids occurrence of the women during pregnancy include the high pre-pregnancy body mass index value,the gynecological discases before pregnancy and the drinking within 1 month before pregnancy.The incidences of adverse pregnancy outcomes and cesarean section of the pregnant women with uterine fibroids during pregnancy increase,which should be prevented and controlled in clinical practice.
作者 邢媛 周雪 季小红 张聪 XING Yuan;ZHOU Xue;JI Xiaohong;ZHANG Cong(Obstetrics and Gynecology HospitalAffiliated to Nanjing Medical University(Nanjing Women and Children's Healthcare Hospital),Nanjing Jiangsu Province,212000)
出处 《中国计划生育学杂志》 2024年第1期146-149,共4页 Chinese Journal of Family Planning
关键词 妊娠期子宫肌瘤 危险因素 不良妊娠结局 相关性 Uterine fibroids during pregnancy Risk factor Adverse pregnancy outcomes Correlation
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