摘要
胃癌患者是发生静脉血栓栓塞(VTE)和出血的高危人群,并且发生VTE的患者常与不良结局有关,因此如何识别和管理胃癌患者的血栓风险成为临床上的难点。胃癌患者发生VTE的风险因素包括年龄、肥胖、外科手术、化学治疗等,识别高风险患者并积极采取预防策略十分必要。预防和治疗VTE的主要策略是使用抗凝药物。该文探讨胃癌患者预防与治疗VTE的指南和近期研究,以帮助临床医生为患者做出个体化决策,最大程度地改善患者的临床结局。
Patients with gastric cancer are at high risk for venous thromboembolism(VTE)and bleeding,and patients who develop VTE are often associated with poor outcomes,making it clinically challenging to identify and manage the risk of thrombosis in patients with gastric cancer.Risk factors for VTE in gastric cancer patients include age,obesity,surgery,chemotherapy,etc.It is essential to identify high-risk patients and adopt aggressive prevention strategies.The main strategy to prevent and treat VTE is the use of anticoagulant drugs.This article discusses guidelines and recent studies for the prevention and treatment of VTE in patients with gastric cancer to help clinicians make individualized decisions for their patients and maximize clinical outcomes for their patients.
作者
郑星月
李炼
武刘芸
尹琪楠
韩丽珠
雷洋
边原
ZHENG Xingyue;LI Lian;WU Liuyun;YIN Qinan;HAN Lizhu;LEI Yang;BIAN Yuan(Department of Pharmacy,Sichuan Provincial People's Hospital/Affiliated Hospital of University of Electronic Science and Technology of China,Sichuan Academy of Medical Sciences,Chengdu 610072,China;Personalized Drug Therapy Key Laboratory of Sichuan Province,Sichuan Provincial People's Hospital/Affiliated Hospital of University of Electronic Science and Technology of China,Sichuan Academy of Medical Sciences,Chengdu 610072,China)
出处
《医药导报》
2024年第2期228-233,共6页
Herald of Medicine
基金
国家重点研发计划(2020YFC2005500)
四川省科技厅自然科学基金资助项目(2022NSFSC0818)
个体化药物治疗四川省重点实验室开放课题(2021ZD01)
四川省干部保健科研课题(川干研ZH2021-20)
中国研究型医院学会研究项目(Y2022FH-YWPJ01-202)。
关键词
抗凝药物
胃癌
静脉血栓栓塞
出血
Anticoagulation
Gastric cancer
Venous thromboembolism
Bleeding
