摘要
附子理中丸方是治疗呕吐泄泻等消化道疾病的常用中药,现代药理研究表明其具有抗炎、调节免疫、修复胃肠黏膜屏障、镇痛等作用,在临床上主要用于胃溃疡、溃疡性结肠炎、慢性腹泻等脾肾阳虚所致的消化道疾病的治疗。溃疡性结肠炎是临床常见的消化道疾病之一,且近年来发病率逐渐升高,由于其具有病程长、难治愈、易反复发作的特点,严重影响患者的生命质量,目前并没有特效的治疗药物。临床研究表明,附子理中丸方对溃疡性结肠炎具有一定的疗效,本文将从临床应用、药理作用与活性成分3个方面对附子理中丸方治疗溃疡性结肠炎的作用进行综述,为其进一步开发应用提供依据。
Traditional Chinese Medicine,such as Fuzi Lizhong Prescription,is frequently used to treat digestive system disorders including vomiting and diarrhea.It possesses anti-inflammatory,immune-regulating,gastrointestinal mucosal barrier repair,analgesic,and other effects,according to contemporary pharmacological investigations.It is primarily utilized in the therapeutic therapy of gastrointestinal tract disorders brought on by chronic diarrhea,ulcerative colitis,gastric ulcers,and various spleen and kidney Yang shortage.One of the frequent gastrointestinal disorders seen in clinics is ulcerative colitis,whose prevalence has progressively risen in recent years.There is no particular medication for therapy since the disease has a protracted course,is difficult to treat,and is prone to recurrence.These factors substantially impair patients' quality of life.Clinical studies have demonstrated that Fuzi Lizhong Prescription can treat ulcerative colitis.In order to establish a foundation for its future research and use,this article investigated the clinical applicability,pharmacological activity,and active components of aconitum rhizome in the treatment of ulcerative colitis.
作者
李依林
左泽平
田颖颖
赵新月
刘闯
于尚玥
裴海鸾
田时秋
王志斌
LI Yilin;ZUO Zeping;TIAN Yingying;ZHAO Xinyue;LIU Chuang;YU Shangyue;PEI Hailuan;TIAN Shiqiu;WANG Zhibin(Beijing University of Chinese Medicine School of Traditional Chinese Medicine,Beijing,102401,China;Beijing Tong Ren Tang Technology Co.,LTD.Pharmaceutical Factory)
出处
《中国中西医结合消化杂志》
CAS
2024年第1期78-83,共6页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
附子理中丸方
溃疡性结肠炎
活性成分
作用机制
Fuzi Lizhong Prescription
ulcerative colitis
active ingredients
mechanism of action
