摘要
单宁酸(tannic acid)存在于五倍子等中药中,是一种简单的水解鞣质类化合物,是许多传统鞣质类药物的关键成分,具有抗氧化、抗炎、抗肿瘤等药理作用,已获得美国食品药品监督管理局的安全认证,并被广泛应用于食品添加剂领域。经纳米化处理后,单宁酸的生物利用度和药效得以显著提高,从而赋予其更大的治疗潜力。在神经保护、抗氧化、抗炎、抗肿瘤等领域,单宁酸及其纳米颗粒表现出广泛的应用前景。通过综述单宁酸及其纳米颗粒在药理研究方面的最新进展,为进一步探讨其在促进人体健康方面的应用提供新思路。
Tannic acid is a simple hydrolyzed tannin compound that exists in Chinese traditional medicine such as Galla Chinensis and has obtained safety certification from the US Food and Drug Administration and is widely used in the field of food additives.At the same time,it is a key component of many traditional tannin drugs and has a wide range of pharmacological effects,such as antioxidant,anti-inflammatory,and anti-tumor properties.After nanoparticle treatment,the bioavailability and efficacy of tannic acid have been significantly improved,endowing it with stronger therapeutic potential.Tannic acid and its nanoparticles have shown broad application prospects in fields such as neuroprotection,antioxidant,antiinflammatory,and anti-tumor.This article aims to review the latest progress in pharmacological research of tannic acid and its nanoparticles,providing important ideas for further exploring the application of tannic acid and its nanoparticles in promoting human health.
作者
王灿
梁如铭
李健
吕薇
李思睿
武世奎
WANG Can;LIANG Ru-ming;LI Jian;LYU Wei;LI Si-rui;WU Shi-kui*(College of Pharmacy,Inner Mongolia Medical University,Hohhot 010110,China)
出处
《中国现代中药》
CAS
2023年第12期2643-2650,共8页
Modern Chinese Medicine
基金
致远人才团队项目(NYTD-2017004)
“三位一体”大学生创新创业培育项目(SWYT2021027)
内蒙古医科大学“青年领创”团队联盟项目(QNLC-2020040)。
关键词
单宁酸
单宁酸纳米颗粒
药理作用
tannic acid
tannic acid nanoparticles
pharmacological effects
