摘要
目的:通过Meta分析比较三氯生涂层与无涂层缝合线在成人开腹手术术后减少手术部位感染的有效性。方法:计算机检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、MedLine、EMbase、the Cochrane Library等数据库中关于三氯生涂层缝合线预防成人开腹手术术后感染效果的文献,检索时限为建库至2022年2月16日。按照纳入与排除标准筛选后,使用RevMan 5.3分析数据。结果:纳入12项研究,共5797例病人。三氯生涂层缝合线及无涂层缝合线的手术部位感染发生率分别为10.4%、13.6%,差异有统计学意义[RR=-0.03,95%CI(-0.06,-0.01),P=0.010];3项研究仅涉及腹膜炎手术,发现抗菌剂涂层缝合线有更好的效果[RR=0.37,95%CI(0.19,0.73),P=0.004]。结论:现有证据表明,三氯生涂层缝合线在降低普外科腹部切口手术部位感染发生率方面具有优势。
Objective:To compare the effectiveness of triclosan coated and uncoated sutures in reducing surgical site infections after adult open surgery through Meta-analysis.Methods:The literature about effectiveness of triclosan coated suture in preventing postoperative infections in adults undergoing open surgery were retrieved from databases such as CNKI,WanFang Database,VIP,CBM,MedLine,EMbase,the Cochrane Library.The retrieval time was from the inception to February 16,2022.After screening according to inclusion and exclusion criteria,the data was analyzed using RevMan 5.3.Results:A total of 5797 patients were included in 12 articles.The incidence of surgical site infection in triclosan coated and uncoated sutures was 10.4%and 13.6%,respectively,with statistically significant differences(RR=-0.03,95%CI―0.06-―0.01,P=0.010);three studies only involved peritonitis surgery and found that antimicrobial coated sutures had better efficacy(RR=0.37,95%CI 0.19-0.73,P=0.004).Conclusion:Current evidence shows that triclosan coated sutures have advantages in reducing the incidence of surgical site infections in general abdominal incisions.
作者
刘子婷
谢玉珍
陈金龙
张爱华
何培亮
LIU Ziting;XIE Yuzhen;CHEN Jinlong;ZHANG Aihua;HE Peiliang(Guangzhou Red Cross Hospital,Guangdong 510220 China)
出处
《循证护理》
2024年第3期386-391,共6页
Chinese Evidence-Based Nursing
基金
广州市科技计划项目,编号:202002030049。
