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牙周炎促进动脉粥样硬化的机制

Mechanisms of action of periodontitis on accelerating atherosclerosis
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摘要 牙周炎作为一种常见病,被认为与许多系统性疾病密切相关,尤其是心血管疾病。动脉粥样硬化是心血管疾病发生发展的基础病变。近年来的研究表明牙周炎可促进动脉粥样硬化的发生与发展。文章回顾牙周炎在促进动脉粥样硬化方面的相关证据,重点探讨其促进动脉粥样硬化的相关机制,为临床诊治提供新思路。 Periodontitis,a common disease,is considered to be closely associated with many systemic diseases,especially cardiovascular disease.Atherosclerosis is the basic pathological change of cardiovascular disease,and recent evidence has indicated that periodontitis promotes the onset and progression of atherosclerosis.This article reviews the roles of periodontitis in accelerating atherosclerosis and highlights the involved mechanisms to provide new strategies for diagnosis and treatment of atherosclerosis.
作者 李华 曲会娟 孟鑫 张雪颖 孙敏敏 郭守东 冀洪海 LI Hua;QU Huijuan;MENG Xin;ZHANG Xueying;SUN Minmin;GUO Shoudong;JI Honghai(School of Stomatology,Weifang Medical University,Weifang,Shandong 261053,China;Department of Stomatology,Affiliated Hospital of Weifang Medical University,Weifang,Shandong 261000,China;School of Pharmacy,Weifang Medical University,Weifang,Shandong 261053,China)
出处 《中国动脉硬化杂志》 CAS 2024年第2期178-184,共7页 Chinese Journal of Arteriosclerosis
基金 国家自然科学基金资助项目(82070469) 山东省自然科学基金青年项目(ZR2022QH273)。
关键词 牙周炎 动脉粥样硬化 牙周病原体 心血管疾病 periodontitis atherosclerosis periodontal pathogenic bacteria cardiovascular disease
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