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An Expanded View of Complex Traits:From Polygenic to Omnigenic

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摘要 A central goal of genetics is to understand the links between genetic variation and disease.Intuitively,one might expect diseasecausing variants to cluster into key pathways that drive disease etiology.But for complex traits,association signals tend to be spread across most of the genome-including near many genes without an obvious connection to disease.
作者 Evan A Boyle
机构地区 不详
出处 《四川生理科学杂志》 2024年第1期139-139,共1页 Sichuan Journal of Physiological Sciences
关键词 TRAITS CLUSTER COMPLEX
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