摘要
目的概述全球HIV疫苗接种策略相关的经济学评价研究,为HIV疫苗接种有关决策和研究提供参考。方法中文以“艾滋病或获得性免疫缺陷综合征”和“疫苗”和“经济学评价或成本效果分析或成本效用分析或成本效益分析”,英文以“Human immunodeficiency virus(HIV)or Acquired immunodeficiency syndrome(AIDS)”和“vaccine or vaccination”和“economic evaluation or cost-effectiveness analysis or cost-utility analysis or cost-benefit analysis or Health technology assessment(HTA)”3组检索词分别组合,在万方数据知识服务平台(万方)、中国医院知识仓库(CHKD)和PubMed数据库,检索截至2022年7月31日的HIV疫苗接种策略经济学评价相关文献,并对文献进行质量评估和综合分析。结果共纳入17篇质量评估良好的文献,综合分析结果提示,无论是艾滋病重点人群或全人群,接种HIV疫苗是节省成本或具有成本效果的策略,可有效减少新发感染并提高人群生命质量。疫苗的有效率、覆盖率、价格和接种后风险性行为的变化等因素影响不同目标人群的接种效果。结论目前HIV疫苗接种策略经济学评价的高质量研究数据较少,研究者可基于真实世界证据开展深入研究。
Objective To summarize the progress in research of economic evaluation of HIV vaccination strategies in the world,and provide reference for future decision-making and research on HIV vaccination.Methods The key words used for literature retrieval were"HIV/AIDS",and"vaccine/vaccination"and"economic evaluation/cost-effectiveness analysis/cost-utility analysis/cost-benefit analysis/HTA".Literatures about the economic evaluation of HIV vaccination strategies published as of July 31,2022,were retrieved from Wanfang Data(Wanfang),China Hospital Knowledge Database(CHKD),and PubMed databases.The quality of the articles was evaluated and analyzed comprehensively.Results A total of 17 study articles with good quality were included.Results from the comprehensive analysis showed that HIV vaccination is a cost-saving or cost-effective strategy for key populations or the whole population.HIV vaccination could effectively reduce new infections and improve the quality of life of population.Factors,such as vaccine efficiency,coverage rate,price,and risk behavior change after vaccination,would affect the vaccination effect in different targeted populations.Conclusions There were limited high-quality research data about the economic evaluation of HIV vaccination strategies.It is necessary to conduct in-depth research based on real-world evidence.
作者
曹雨馨
葛启伟
庄勋
Cao Yuxin;Ge Qiwei;Zhuang Xun(Department of Epidemiology and Health Statistics,School of Public Health,Nantong University,Nantong 226019,China)
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2024年第1期155-161,共7页
Chinese Journal of Epidemiology
基金
国家重点研发计划(2022YFC2304901)
南通市科技局社会民生科技项目(MS12021099)
江苏省研究生创新项目(KYCX23_3435)。
