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孕妇微生态菌群与妊娠期并发症和不良妊娠结局相关性的研究进展

Research progress in the association of maternal microbiota with pregnancy complications and adverse pregnancy outcomes
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摘要 孕妇微生态菌群紊乱与母胎结局有一定的相关性。随着微生物组学技术的发展,这一领域的研究逐渐深入。本文对孕妇微生态菌群与妊娠期并发症和不良妊娠结局的相关性进行探究,并对其作用机制的研究进展进行总结和综述,结果显示孕妇微生态菌群紊乱可能会增加多种妊娠期并发症和不良妊娠结局的风险,但相关生物学机制的研究较少。医务人员应更深入地了解和研究孕妇微生态菌群与妊娠期并发症和不良妊娠结局的相关性,以有助于孕产妇和新生儿的健康诊断及早期预防与干预。 There is a certain association between reproductive tract infection and maternal-fetal outcome.With the development of microbiome technology,in-depth research in this field is gradually increasing.This paper explored the correlation between pregnancy maternal microbiota and complications and adverse outcomes,and summarized the research progress of its mechanism.The results suggest that maternal microbiota dysbacteriosis increase the risk of multiple pregnancy complications and adverse pregnancy outcomes,but there is limited research on the relative biological mechanisms.It is necessary to understand and study the correlation between pregnancy maternal microbiota and complications and adverse outcomes more deeply,so as to contribute to the health diagnosis,early prevention and intervention of pregnant women and newborns.
作者 孙盈利 安映霖 吴天晨 魏瑗 SUN Ying Li;AN Ying Lin;WU Tian Chen;WEI Yuan(Peking University Third Hospital,Beijing 100191,China)
出处 《中国妇幼卫生杂志》 2024年第1期67-71,共5页 Chinese Journal of Women and Children Health
基金 北京大学第三医院院队列建设项目(BYSYDL2021004)。
关键词 孕妇微生态菌群 妊娠期并发症 不良妊娠结局 maternal microbiota complications of pregnancy adverse pregnancy outcomes
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