摘要
目的 分析消化道早癌及癌前病变患者的临床和病理特征。方法 回顾1021例消化道早癌及癌前病变患者临床资料,对其发病部位、病灶特征和病理结果等进行分析。结果 共收集病例1021例,男女比例为1.60:1,发病部位分布范围自食管至直肠均有发现,食管、胃、结直肠和十二指肠中,于结直肠发现例数最多[82.86%(846/1021)];按详细部位排列,最多位于乙状结肠,其次为横结肠、升结肠、直肠、胃窦、食管、降乙交界、降结肠、直乙交界、盲肠、结肠脾区、胃体、结肠肝区、十二指肠、贲门、胃底、幽门,大部分病灶尺寸<1 cm,占57.88%,所有病灶中以Ⅰ型病灶为主;LST(侧向发育型肿瘤)病灶好发于右半结肠;所有病理结果中,高级别瘤变占比50.44%,检出最多位于乙状结肠;原位癌比例仅占7.15%,在直肠及直乙交界检出最高。结论 消化道早癌及癌前病变的发现范围分布自食管至直肠,结直肠检出比例高,最常见于乙状结肠,LST好发于右半结肠,原位癌不易被发现。
Objective To analyze the pathogenic sites and pathological features of early-stage gastrointestinal cancer and precancerous lesions.Methods The clinical data of 1021 patients with early-stage gastrointestinal cancer and precancerous lesions were reviewed to analyze the pathogenic sites and pathological features.Results A total of 1021 cases were collected,and the male to female ratio was 1.60:1.0.The lesions were found from esophagus to rectum.Among the oesophagus,stomach,colorectum and duodenum lesions,colorectum lesions were found in the most cases [82.86%(846/1021)].Most of the lesions were located in the sigmoid colon,followed by transverse colon,ascending colon,rectum,gastric antrum,esophagus,descending and sigmoid colon junction,descending colon,rectosigmoid junction,cecum,splenic flexure,stomach body,hepatic flexure,duodenum,cardia,fundus,and pylorus.Most of the lesions(57.88%) were less than 1 cm in size.Type I lesions were predominant among all the lesions.Laterally spreading tumor(LST) mostly occurs in the right colon.Of all the pathological results,high-grade neoplasia accounted for 50.44%,and most of them were found in the sigmoid colon.The carcinoma in situ only accounted for 7.15%,and most of them were detected in the rectum and the rectosigmoid junction.Conclusion Early-stage gastrointestinal cancer and precancerous lesions range from the esophagus to the rectum,and most of them distribute in the colorectum,especially the sigmoid colon.LST usually occurs in the right colon,and carcinoma in situ is not easy to be found.
作者
赵振刚
ZHAO Zhen-gang(Department of Digestive Hepatology,Tianjin Third Central Hospital,Tianjin Key Laboratory of Extracorporeal Life Support for Severe Diseases,Tianjin Artificial Cell Engineering Technology Research Center,Tianjin Institute of Hepatobiliary Diseases,Tianjin 300170,China)
出处
《实用临床医学（江西）》
CAS
2023年第6期1-6,14,共7页
Practical Clinical Medicine
基金
天津市医学重点学科(专科)建设项目资助(TJYXZDXK-034A)
天津市卫生健康科技项目重点学科专项资助(TJWJ2022XK029)。
关键词
消化道早癌
癌前病变
发病部位
病理
early-stage gastrointestinal cancer
precancerous lesions
pathogenic site
pathology
