摘要
目的:探究不同肠内营养方式对口腔癌根治性切除术并同期行修复重建术后术区感染的影响。方法:回顾性分析2018年1月~2023年1月就诊于新疆医科大学第一附属医院口腔颌面肿瘤外科接受口腔癌根治性切除术并同期行修复重建的患者的临床资料,根据给予的不同肠内营养方式,将纳入病例分为预防性经皮胃造瘘组(n=26)、鼻饲管组(n=54)及经口进食组(n=33)。比较3组患者手术治疗后术区感染率、皮瓣坏死率情况。结果:预防性经皮胃造瘘组患者术区感染率显著低于鼻饲管组和经口进食组(P<0.05);3组间皮瓣坏死率比较差异无统计学意义(P>0.05)。术后6周患者体重指数、总蛋白、白蛋白、肌酐、红细胞压积值与入院时测量的差值在3组间比较存在明显差异(P<0.01)。结论:预防性经皮胃造瘘可以有效降低口腔癌根治性切除术并同期行修复重建术后皮瓣感染率,值得临床推广。
Objective:To investigate the effects of different types of enteral nutrition on surgical site infection after extensive resection and simultaneous reconstruction of patients with oral cancer.Methods:The data of patients who underwent oral cancer radical resection along with reconstruction at Oncological Department of Oral and Maxillofacial Surgery,the First Affiliated Hospital of Xinjiang Medical University from January 2018 to January 2023 were retrospectively analyzed.According to different enteral nutrition,the patients were divided into the group of prophylactic percutaneous endoscopic gastrostomy(26 cases),group of nasogastric tube(54 cases),and group of oral feeding(33 cases).The changes of postoperative surgical site infection rate and flap necrosis rate among three groups were analyzed through SPSS 25.0 statistical software.Results:The postoperative surgical site infection rate in the group treated with prophylactic percutaneous endoscopic gastrostomy was significantly lower than that in nasogastric tube group and oral feeding group(P<0.05).The rate of flap necrosis had no statistical significance among three groups(P>0.05).The difference of body mass index,total protein,albumin,creatinine,and hematocrit between admission and 6 weeks after surgery was significantly differ-ent among three groups(P<0.01).Conclusion:Prophylactic percutaneous endoscopic gastrostomy can effectively reduce the flap infection rate after extensive resection along with simultaneous reconstruction of oral cancer cases,which is worthy of clinical promotion.
作者
帕热克江·帕塔尔
李晨曦
克热木·阿巴司
胡露露
方昌
龚忠诚
Parekejiang·PATAER;LI Chenxi;Keremu·ABA-SI;HU Lulu;FANG Chang;GONG Zhongcheng(Department of Oral and Maxillofacial Oncolo-gy&Surgery,School/Hospital of Stomatology,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;Stomatological Research Institute of Xinjiang Uygur Autonomous Region,Urumqi 830054,China;Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration,School of Stomatology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technol-ogy,Wuhan 430022,China.)
出处
《口腔医学研究》
CAS
CSCD
北大核心
2024年第1期29-34,共6页
Journal of Oral Science Research
基金
国家自然科学基金(编号:82360481)
口腔颌面发育与再生湖北省重点实验室开放课题基金(编号:2022kqhm008)
新疆维吾尔自治区科研创新项目(编号:XJ2023G174)。
关键词
口腔癌
修复重建
术区感染
预防性经皮胃造瘘
oral cancer
repair and reconstruction
surgical site infection
prophylactic percutaneous endo-scopic gastrostomy
