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超声乳化白内障吸除术配合房角分离术治疗原发性急性闭角型青光眼合并白内障的临床效果和安全性分析

Clinical effect and safety analysis of phacoemulsification combined with goniosynechialysis in the treatment of primary acute angle-closure glaucoma complicated with cataract
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摘要 目的评定超声乳化白内障吸除术配合房角分离术治疗原发性急性闭角型青光眼合并白内障患者的效果及安全性。方法选取100例原发性急性闭角型青光眼合并白内障患者为研究对象,随机分为试验组和对照组,每组50例。试验组施以超声乳化白内障吸除术配合房角分离术治疗,对照组施以超声乳化白内障吸除术配合小梁切除术治疗。比较两组治疗效果,术前、术后3个月最佳矫正视力、眼压、前房深度、前房角宽度与并发症发生情况。结果试验组总有效率(98.00%)较对照组(86.00%)更高,差异具有统计学意义(P<0.05);术前,试验组最佳矫正视力为(0.23±0.08)、眼压为(43.60±3.45)mm Hg(1 mm Hg=0.133 kPa)、前房深度为(2.35±0.27)mm、前房角宽度为(13.52±2.63)°,对照组分别为(0.24±0.10)、(43.52±4.17)mm Hg、(2.46±0.35)mm、(13.44±3.07)°;术后3个月,试验组最佳矫正视力为(0.47±0.03)、眼压为(15.26±1.75)mm Hg、前房深度为(3.30±0.14)mm、前房角宽度为(30.21±1.27)°,对照组分别为(0.38±0.04)、(18.38±2.07)mm Hg、(3.02±0.25)mm、(26.35±1.14)°。两组术后3个月最佳矫正视力、前房深度、前房角宽度均高于术前,眼压水平均低于术前,且试验组术后3个月最佳矫正视力、前房深度、前房角宽度更高,眼压水平更低,差异具有统计学意义(P<0.05);试验组并发症发生率(6.00%)较对照组(20.00%)更低,差异具有统计学意义(P<0.05)。结论原发性急性闭角型青光眼合并白内障患者施以超声乳化白内障吸除术配合小梁切除术方案与配合房角分离术方案均能取得一定效果,其中超声乳化白内障吸除术配合房角分离术方案的应用能获取优质的效果,更好改善最佳矫正视力、眼压、前房深度、前房角宽度等指标水平,减少并发症发生的几率,意义重大。 Objective To evaluate the effect and safety of phacoemulsification combined with goniosynechialysis in the treatment of primary acute angle-closure glaucoma complicated with cataract.Methods 100 patients with primary acute angle-closure glaucoma and cataract were selected as the study subjects.They were randomly divided into an experimental group and a control group,each with 50 cases.The experimental group was treated with phacoemulsification and goniosynechialysis,and the control group was treated with phacoemulsification and trabeculectomy.The treatment effect,the best corrected visual acuity,intraocular pressure,anterior chamber depth,anterior chamber angle width before and 3 months after surgery and complications were compared between the two groups.Results The total effective rate of the experimental group(98.00%)was higher than the control group(86.00%),and the difference was statistically significant(P<0.05).Before surgery,the best corrected visual acuity,intraocular pressure,anterior chamber depth,anterior chamber angle width in the experimental group were(0.23±0.08),(43.60±3.45)mm Hg(1 mm Hg=0.133 kPa),(2.35±0.27)mm,and(13.52±2.63)°,and those in the control group were(0.24±0.10),(43.52±4.17)mm Hg,(2.46±0.35)mm,and(13.44±3.07)°,respectively.After 3 months of surgery,the best corrected visual acuity,intraocular pressure,anterior chamber depth,anterior chamber angle width in the experimental group were(0.47±0.03),(15.26±1.75)mm Hg,(3.30±0.14)mm,and(30.21±1.27)°,and those in the control group were(0.38±0.04),(18.38±2.07)mm Hg,(3.02±0.25)mm,and(26.35±1.14)°,respectively.At 3 months after surgery,the best corrected visual acuity,anterior chamber depth,and anterior chamber angle width in both groups were higher than those before surgery,and the intraocular pressure was lower than that before surgery;and the experimental group had higher best corrected visual acuity,anterior chamber depth and anterior chamber angle width,and lower intraocular pressure;the difference was statistically significant(P<0.05).The incidence of complications in the experimental group(6.00%)was lower than the control group(20.00%),and the difference was statistically significant(P<0.05).Conclusion For patients with primary acute angle-closure glaucoma complicated with cataract,phacoemulsification combined with trabeculectomy and goniosynechialysis can achieve certain results,and the application of phacoemulsification combined with goniosynechialysis can obtain high-quality results.It is of great significance to improve the best corrected visual acuity,intraocular pressure,anterior chamber depth,anterior chamber angle width and other indicators,and reduce the probability of complications.
作者 霍显青 HUO Xian-qing(Linqing Hospital of Traditional Chinese Medicine,Linqing 252600,China)
出处 《中国实用医药》 2024年第3期60-63,共4页 China Practical Medicine
关键词 超声乳化白内障吸除术 小梁切除术 房角分离术 原发性急性闭角型青光眼 白内障 Phacoemulsification Trabeculectomy Goniosynechialysis Primary acute angle-closure glaucoma Cataract
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